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人CRYGC(NM_020989)ORF克隆
人CRYGC(NM_020989)ORF克隆
会员等级价V
已售 5 件 | 评价 0 人次 | 关注度 297
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  • 商品货号:F131238
  • accession:NM_020989
  • 基因别名:CRYGC
  • 基因描述:Homo sapiens crystallin, gamma C (CRYGC), mRNA.
  • 载体: 现货载体
  • CDS区长度:525
  • 翻译后氨基酸长度:174
  • 基因简介:Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation. [provided by RefSeq, Jul 2008]
  • 载体信息:自有图片地址
  • 规格:10ul 质粒
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