- accession:NM_001185090
- 基因别名:NR1; MRD8; GluN1; NMDA1; NMDAR1
- 基因描述:Homo sapiens glutamate receptor, ionotropic, N-methyl D-aspartate 1 (GRIN1), transcript variant NR1-4, mRNA.
- 载体:现货载体
- CDS区长度:2832
- 翻译后氨基酸长度:943
- TranscriptVariant:This variant (NR1-4) contains an alternate coding segment and uses a different splice site in the 3' coding region, compared to variant NR1-3. The resulting protein (isoform NR1-4) is longer and has a distinct C-terminus when it is compared to isoform NR1-3. This variant has also been named isoform 4b or NMDAR1-4b.
- 基因简介:The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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