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- 商品货号：G165560
- accession：NM_001198999
- 基因描述：Homo sapiens sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D (SEMA6D), transcript variant 7, mRNA.
- 载体：现货载体
- CDS区长度：3036
- 翻译后氨基酸长度：1011
- TranscriptVariant：This variant (7) uses an alternative splice site on one exon, lacks two internal exons, and differs in the 5' UTR, compared to variant 4. The encoded isoform (1) is missing an internal region compared to isoform 4 and contains an internal segment unique to this isoform. Variants 1 and 7 both encode the same isoform (1).
- 基因简介：Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding, fasciculation and branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphorin domain allow classification into distinct subfamilies. Results demonstrate that transmembrane semaphorins, like the secreted ones, can act as repulsive axon guidance cues. This gene encodes a class 6 vertebrate transmembrane semaphorin that demonstrates alternative splicing. Several transcript variants have been identified and expression of the distinct encoded isoforms is thought to be regulated in a tissue- and development-dependent manner. [provided by RefSeq, Nov 2010]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
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