- accession:NM_002728
- 基因别名:PRG2
- 基因描述:Homo sapiens proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) (PRG2), transcript variant 1, mRNA.
- 载体: 现货载体
- CDS区长度:669
- 翻译后氨基酸长度:222
- TranscriptVariant:This variant (1) represents the predominant transcript, and encodes the longer isoform (1).
- 基因简介:The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
- 载体信息:自有图片地址
- 规格:10ul 质粒
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