• 商品货号：G100329

• accession：NM_001515
• 基因别名：GTF2H2
• 基因描述：Homo sapiens general transcription factor IIH, polypeptide 2, 44kDa (GTF2H2), mRNA.
• 载体：现货载体
• CDS区长度：1188
• 翻译后氨基酸长度：395
• 基因简介：This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This gene is within the telomeric copy of the duplication. Deletion of this gene sometimes accompanies deletion of the neighboring SMN1 gene in spinal muscular atrophy (SMA) patients but it is unclear if deletion of this gene contributes to the SMA phenotype. This gene encodes the 44 kDa subunit of RNA polymerase II transcription initiation factor IIH which is involved in basal transcription and nucleotide excision repair. Transcript variants for this gene have been described, but their full length nature has not been determined. A second copy of this gene within the centromeric copy of the duplication has been described in the literature. It is reported to be different by either two or four base pairs; however, no sequence data is currently available for the centromeric copy of the gene. [provided by RefSeq, Jul 2008]
• 规格：10ul 质粒

CDS区参考序列： 点击查看序列

ATGGATGAAGAACCTGAAAGAACTAAGCGATGGGAAGGAGGCTATGAAAGAACATGGGAGATTCTTAAAG
AAGATGAATCTGGATCACTTAAAGCTACAATAGAAGACATTCTATTCAAGGCAAAGAGAAAAAGAGTATT
TGAGCACCATGGACAAGTTCGACTTGGAATGATGCGCCACCTTTATGTGGTAGTAGATGGATCAAGAACA
ATGGAAGACCAAGATTTAAAGCCTAATAGACTGACGTGTACTTTAAAGTTGTTGGAATACTTTGTAGAGG
AATATTTTGATCAAAATCCTATTAGTCAGATTGGAATAATTGTAACTAAGAGTAAAAGAGCTGAAAAATT
GACTGAACTTTCAGGAAACCCAAGAAAACATATAACGTCTTTGAAGAAAGCTGTGGATATGACCTGCCAT
GGAGAGCCATCTCTTTATAATTCCCTAAGCATAGCTATGCAGACTCTAAAACACATGCCTGGACATACAA
GTCGAGAAGTACTAATCATCTTTAGCAGCCTTACAACTTGCGATCCATCTAATATTTATGATCTAATCAA
GACCCTAAAGGCAGCTAAAATTAGAGTATCTGTTATTGGATTGTCTGCAGAAGTTCGCGTTTGCACTGTA
CTTGCTCGTGAAACTGGTGGCACGTACCATGTTATTTTAGATGAAAGCCATTACAAAGAGTTGCTCACAC
ATCATGTTAGTCCTCCTCCTGCTAGCTCAAGTTCTGAATGCTCACTTATTCGTATGGGATTTCCTCAGCA
CACCATTGCTTCTTTATCTGACCAGGATGCAAAACCCTCTTTCAGCATGGCGCATTTGGATGGCAATACT
GAGCCAGGGCTTACATTAGGAGGCTATTTCTGCCCACAGTGTCGGGCAAAGTACTGTGAGCTACCTGTTG
AGTGTAAAATCTGTGGTCTTACTTTGGTGTCTGCTCCCCACTTGGCACGGTCTTACCATCATTTGTTTCC
TTTGGATGCTTTTCAAGAAATTCCCCTAGAAGAATATAATGGAGAAAGATTTTGTTATGGATGTCAGGGG
GAATTGAAAGACCAACATGTTTATGTTTGTGCTGTGTGCCAAAATGTTTTCTGTGTGGACTGTGATGTTT
TTGTTCATGATTCTCTACACTGTTGCCCTGGCTGTATTCATAAGATTCCAGCTCCTTCAGGTGTTTGA

翻译后氨基酸参数序列： 点击查看序列

ATGGATGAAGAACCTGAAAGAACTAAGCGATGGGAAGGAGGCTATGAAAGAACATGGGAGATTCTTAAAG
AAGATGAATCTGGATCACTTAAAGCTACAATAGAAGACATTCTATTCAAGGCAAAGAGAAAAAGAGTATT
TGAGCACCATGGACAAGTTCGACTTGGAATGATGCGCCACCTTTATGTGGTAGTAGATGGATCAAGAACA
ATGGAAGACCAAGATTTAAAGCCTAATAGACTGACGTGTACTTTAAAGTTGTTGGAATACTTTGTAGAGG
AATATTTTGATCAAAATCCTATTAGTCAGATTGGAATAATTGTAACTAAGAGTAAAAGAGCTGAAAAATT
GACTGAACTTTCAGGAAACCCAAGAAAACATATAACGTCTTTGAAGAAAGCTGTGGATATGACCTGCCAT
GGAGAGCCATCTCTTTATAATTCCCTAAGCATAGCTATGCAGACTCTAAAACACATGCCTGGACATACAA
GTCGAGAAGTACTAATCATCTTTAGCAGCCTTACAACTTGCGATCCATCTAATATTTATGATCTAATCAA
GACCCTAAAGGCAGCTAAAATTAGAGTATCTGTTATTGGATTGTCTGCAGAAGTTCGCGTTTGCACTGTA
CTTGCTCGTGAAACTGGTGGCACGTACCATGTTATTTTAGATGAAAGCCATTACAAAGAGTTGCTCACAC
ATCATGTTAGTCCTCCTCCTGCTAGCTCAAGTTCTGAATGCTCACTTATTCGTATGGGATTTCCTCAGCA
CACCATTGCTTCTTTATCTGACCAGGATGCAAAACCCTCTTTCAGCATGGCGCATTTGGATGGCAATACT
GAGCCAGGGCTTACATTAGGAGGCTATTTCTGCCCACAGTGTCGGGCAAAGTACTGTGAGCTACCTGTTG
AGTGTAAAATCTGTGGTCTTACTTTGGTGTCTGCTCCCCACTTGGCACGGTCTTACCATCATTTGTTTCC
TTTGGATGCTTTTCAAGAAATTCCCCTAGAAGAATATAATGGAGAAAGATTTTGTTATGGATGTCAGGGG
GAATTGAAAGACCAACATGTTTATGTTTGTGCTGTGTGCCAAAATGTTTTCTGTGTGGACTGTGATGTTT
TTGTTCATGATTCTCTACACTGTTGCCCTGGCTGTATTCATAAGATTCCAGCTCCTTCAGGTGTTTGA