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- 商品货号：G100761
- accession：NM_001185073
- 基因别名：CLDN12
- 基因描述：Homo sapiens claudin 12 (CLDN12), transcript variant 2, mRNA.
- 载体：现货载体
- CDS区长度：735
- 翻译后氨基酸长度：244
- TranscriptVariant：This variant (2) uses an alternate splice site and lacks an exon in the 5' UTR, as compared to variant 1.
- 基因简介：This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is expressed in the inner ear and bladder epithelium, and it is over-expressed in colorectal carcinomas. This protein and claudin 2 are critical for vitamin D-dependent Ca2+ absorption between enterocytes. Multiple alternatively spliced transcript variants encoding the same protein have been found.[provided by RefSeq, Sep 2011]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
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