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人ENO1(NM_001428)ORF克隆
人ENO1(NM_001428)ORF克隆
  • 商品货号:FO103918
  • 已售 9 件 | 评价 0 人次 | 关注度 778
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    • accession:NM_001428
    • 基因别名:ENO1
    • 基因描述:Homo sapiens enolase 1, (alpha) (ENO1), transcript variant 1, mRNA.
    • 载体: 现货载体
    • CDS区长度:1305
    • 翻译后氨基酸长度:434
    • TranscriptVariant:This variant (1) encodes the longer isoform (1), which is localized to the cytosol, and has alpha-enolase activity. It has been reported that the monomeric form of this isoform functions as a structural lens protein (tau-crystallin), and the dimeric form as an enolase (PMID:2462567).
    • 基因简介:This gene encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase in addition, functions as a structural lens protein (tau-crystallin) in the monomeric form. Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy. [provided by RefSeq, Jan 2011]
    • 载体信息:自有图片地址
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列