- accession:NM_133439
- 基因别名:TADA2A
- 基因描述:Homo sapiens transcriptional adaptor 2A (TADA2A), transcript variant 2, mRNA.
- 载体: 现货载体
- CDS区长度:918
- 翻译后氨基酸长度:305
- TranscriptVariant:This variant (2) represents an alternate transcript termination and polyadenylation site. This results in a shorter isoform (b) which has a distinct C-terminus.
- 基因简介:Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. Several alternatively spliced transcript variants encoding different isoforms of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Oct 2009]
- 载体信息:自有图片地址
- 规格:10ul 质粒
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