• accession：NM_003211
• 基因别名：TDG
• 基因描述：Homo sapiens thymine-DNA glycosylase (TDG), mRNA.
• 载体：现货载体
• CDS区长度：1233
• 翻译后氨基酸长度：410
• 基因简介：The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12. [provided by RefSeq, Jul 2008]
• 规格：10ul 质粒

CDS区参考序列： 点击查看序列

ATGGAAGCGGAGAACGCGGGCAGCTATTCCCTTCAGCAAGCTCAAGCTTTTTATACGTTTCCATTTCAAC
AACTGATGGCTGAAGCTCCTAATATGGCAGTTGTGAATGAACAGCAAATGCCAGAAGAAGTTCCAGCCCC
AGCTCCTGCTCAGGAACCAGTGCAAGAGGCTCCAAAAGGAAGAAAAAGAAAACCCAGAACAACAGAACCA
AAACAACCAGTGGAACCCAAAAAACCTGTTGAGTCAAAAAAATCTGGCAAGTCTGCAAAATCAAAAGAAA
AACAAGAAAAAATTACAGACACATTTAAAGTAAAAAGAAAAGTAGACCGTTTTAATGGTGTTTCAGAAGC
TGAACTTCTGACCAAGACTCTCCCCGATATTTTGACCTTCAATCTGGACATTGTCATTATTGGCATAAAC
CCGGGACTAATGGCTGCTTACAAAGGGCATCATTACCCTGGACCTGGAAACCATTTTTGGAAGTGTTTGT
TTATGTCAGGGCTCAGTGAGGTCCAGCTGAACCATATGGATGATCACACTCTACCAGGGAAGTATGGTAT
TGGATTTACCAACATGGTGGAAAGGACCACGCCCGGCAGCAAAGATCTCTCCAGTAAAGAATTTCGTGAA
GGAGGACGTATTCTAGTACAGAAATTACAGAAATATCAGCCACGAATAGCAGTGTTTAATGGAAAATGTA
TTTATGAAATTTTTAGTAAAGAAGTTTTTGGAGTAAAGGTTAAGAACTTGGAATTTGGGCTTCAGCCCCA
TAAGATTCCAGACACAGAAACTCTCTGCTATGTTATGCCATCATCCAGTGCAAGATGTGCTCAGTTTCCT
CGAGCCCAAGACAAAGTTCATTACTACATAAAACTGAAGGACTTAAGAGATCAGTTGAAAGGCATTGAAC
GAAATATGGACGTTCAAGAGGTGCAATATACATTTGACCTACAGCTTGCCCAAGAGGATGCAAAGAAGAT
GGCTGTTAAGGAAGAAAAATATGATCCAGGTTATGAGGCAGCATATGGTGGTGCTTACGGAGAAAATCCA
TGCAGCAGTGAACCTTGTGGCTTCTCTTCAAATGGGCTAATTGAGAGCGTGGAGTTAAGAGGAGAATCAG
CTTTCAGTGGCATTCCTAATGGGCAGTGGATGACCCAGTCATTTACAGACCAAATTCCTTCCTTTAGTAA
TCACTGTGGAACACAAGAACAGGAAGAAGAAAGCCATGCTTAA

翻译后氨基酸参数序列： 点击查看序列

ATGGAAGCGGAGAACGCGGGCAGCTATTCCCTTCAGCAAGCTCAAGCTTTTTATACGTTTCCATTTCAAC
AACTGATGGCTGAAGCTCCTAATATGGCAGTTGTGAATGAACAGCAAATGCCAGAAGAAGTTCCAGCCCC
AGCTCCTGCTCAGGAACCAGTGCAAGAGGCTCCAAAAGGAAGAAAAAGAAAACCCAGAACAACAGAACCA
AAACAACCAGTGGAACCCAAAAAACCTGTTGAGTCAAAAAAATCTGGCAAGTCTGCAAAATCAAAAGAAA
AACAAGAAAAAATTACAGACACATTTAAAGTAAAAAGAAAAGTAGACCGTTTTAATGGTGTTTCAGAAGC
TGAACTTCTGACCAAGACTCTCCCCGATATTTTGACCTTCAATCTGGACATTGTCATTATTGGCATAAAC
CCGGGACTAATGGCTGCTTACAAAGGGCATCATTACCCTGGACCTGGAAACCATTTTTGGAAGTGTTTGT
TTATGTCAGGGCTCAGTGAGGTCCAGCTGAACCATATGGATGATCACACTCTACCAGGGAAGTATGGTAT
TGGATTTACCAACATGGTGGAAAGGACCACGCCCGGCAGCAAAGATCTCTCCAGTAAAGAATTTCGTGAA
GGAGGACGTATTCTAGTACAGAAATTACAGAAATATCAGCCACGAATAGCAGTGTTTAATGGAAAATGTA
TTTATGAAATTTTTAGTAAAGAAGTTTTTGGAGTAAAGGTTAAGAACTTGGAATTTGGGCTTCAGCCCCA
TAAGATTCCAGACACAGAAACTCTCTGCTATGTTATGCCATCATCCAGTGCAAGATGTGCTCAGTTTCCT
CGAGCCCAAGACAAAGTTCATTACTACATAAAACTGAAGGACTTAAGAGATCAGTTGAAAGGCATTGAAC
GAAATATGGACGTTCAAGAGGTGCAATATACATTTGACCTACAGCTTGCCCAAGAGGATGCAAAGAAGAT
GGCTGTTAAGGAAGAAAAATATGATCCAGGTTATGAGGCAGCATATGGTGGTGCTTACGGAGAAAATCCA
TGCAGCAGTGAACCTTGTGGCTTCTCTTCAAATGGGCTAATTGAGAGCGTGGAGTTAAGAGGAGAATCAG
CTTTCAGTGGCATTCCTAATGGGCAGTGGATGACCCAGTCATTTACAGACCAAATTCCTTCCTTTAGTAA
TCACTGTGGAACACAAGAACAGGAAGAAGAAAGCCATGCTTAA