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- accession：NM_001257328
- 基因别名：ARRB2
- 基因描述：Homo sapiens arrestin, beta 2 (ARRB2), transcript variant 3, mRNA.
- 载体：现货载体
- CDS区长度：1293
- 翻译后氨基酸长度：430
- TranscriptVariant：This variant (3) represents the longest transcript and encodes the longest isoform (3).
- 基因简介：Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
