- accession:NM_003461
- 基因别名:ZYX
- 基因描述:Homo sapiens zyxin (ZYX), transcript variant 1, mRNA.
- 载体:现货载体
- CDS区长度:1719
- 翻译后氨基酸长度:572
- TranscriptVariant:This variant (1) represents the longer transcript. Variants 1 and 2 encode the same isoform.
- 基因简介:Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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