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- accession：NM_176786
- 基因别名：IL9R
- 基因描述：Homo sapiens interleukin 9 receptor (IL9R), transcript variant 2, mRNA.
- 载体：现货载体
- CDS区长度：1029
- 翻译后氨基酸长度：342
- TranscriptVariant：This variant (2) differs in the 5' and 3' UTR and has multiple coding region differences, compared to variant 1. Some of these differences result in translational frameshifts. The resulting isoform (2) has distinct N- and C-termini and is shorter than isoform 1.
- 基因简介：The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested an association of this gene with the development of asthma. Multiple pseudogenes on chromosome 9, 10, 16, and 18 have been described. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
