×
![]()
- accession：NM_001207049
- 基因别名：BACE1
- 基因描述：Homo sapiens beta-site APP-cleaving enzyme 1 (BACE1), transcript variant f, mRNA.
- 载体：现货载体
- CDS区长度：1131
- 翻译后氨基酸长度：376
- TranscriptVariant：This variant (f) lacks two exons from the 5' end and has an alternate 5' exon and an alternate splice site in the coding region, compared to variant a. The resulting isoform (F) has a shorter and distinct N-terminus and lacks an internal segment, compared to isoform A.
- 基因简介：Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
