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人 CYP1A2 (NM_000761) cDNA克隆
人 CYP1A2 (NM_000761) cDNA克隆
  • 商品货号:FC134363
  • 已售 1 件 | 评价 0 人次 | 关注度 289
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    • accession:NM_000761
    • 基因别名:CYP1A2
    • 基因描述:Homo sapiens cytochrome P450, family 1, subfamily A, polypeptide 2 (CYP1A2), mRNA.
    • 载体:现货载体
    • CDS区长度:1551
    • 翻译后氨基酸长度:516
    • 基因简介:This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region. [provided by RefSeq, Jul 2008]
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列