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人HCK(NM_001172131)ORF克隆
人HCK(NM_001172131)ORF克隆
  • 商品货号:FO113863
  • 已售 3 件 | 评价 0 人次 | 关注度 422
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    • accession:NM_001172131
    • 基因别名:HCK
    • 基因描述:Homo sapiens hemopoietic cell kinase (HCK), transcript variant 2, mRNA.
    • 载体: 现货载体
    • CDS区长度:1515
    • 翻译后氨基酸长度:504
    • TranscriptVariant:This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. This variant encodes two isoforms due to the use of alternative translation initiation codons, as demonstrated in PMIDs 1875927 and 7791757. The longer isoform (c) is derived from an upstream non-AUG (CUG) start codon, while the shorter isoform (d) is derived from a downstream AUG start codon. The shorter isoform (d) is represented in this RefSeq, and is overall shorter, compared to isoform a.
    • 基因简介:The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon. [provided by RefSeq, Feb 2010]
    • 载体信息:自有图片地址
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列