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人KCNA3(NM_002232)ORF克隆
人KCNA3(NM_002232)ORF克隆
  • 商品货号:FO114014
  • 已售 3 件 | 评价 0 人次 | 关注度 545
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    • accession:NM_002232
    • 基因别名:KCNA3
    • 基因描述:Homo sapiens potassium voltage-gated channel, shaker-related subfamily, member 3 (KCNA3), transcript variant 1, mRNA.
    • 载体: 现货载体
    • CDS区长度:1728
    • 翻译后氨基酸长度:575
    • 基因简介:Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. It plays an essential role in T-cell proliferation and activation. This gene appears to be intronless and it is clustered together with KCNA2 and KCNA10 genes on chromosome 1. [provided by RefSeq, Jul 2008]
    • 载体信息:自有图片地址
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列