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人ORC2(NM_006190)ORF克隆
人ORC2(NM_006190)ORF克隆
会员等级价V
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  • 商品货号:F112341
  • accession:NM_006190
  • 基因别名:ORC2
  • 基因描述:Homo sapiens origin recognition complex, subunit 2 (ORC2), transcript variant 1, mRNA.
  • 载体: 现货载体
  • CDS区长度:1734
  • 翻译后氨基酸长度:577
  • TranscriptVariant:This variant (1) encodes a functional protein.
  • 基因简介:The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. This protein forms a core complex with ORC3, -4, and -5. It also interacts with CDC45 and MCM10, which are proteins known to be important for the initiation of DNA replication. This protein has been demonstrated to specifically associate with the origin of replication of Epstein-Barr virus in human cells, and is thought to be required for DNA replication from viral origin of replication. Alternatively spliced transcript variants have been found, one of which is a nonsense-mediated mRNA decay candidate. [provided by RefSeq, Oct 2010]
  • 载体信息:自有图片地址
  • 规格:10ul 质粒
CDS区参考序列: 点击查看序列
翻译后氨基酸参数序列: 点击查看序列