- accession:NM_001164816
- 基因别名:ACIN1
- 基因描述:Homo sapiens apoptotic chromatin condensation inducer 1 (ACIN1), transcript variant 4, mRNA.
- 载体:现货载体
- CDS区长度:1845
- 翻译后氨基酸长度:614
- TranscriptVariant:This variant (4) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (4), also known as ACINUS-S', has a distinct N-terminus and is shorter than isoform 1.
- 基因简介:Apoptosis is defined by several morphologic nuclear changes, including chromatin condensation and nuclear fragmentation. This gene encodes a nuclear protein that induces apoptotic chromatin condensation after activation by caspase-3, without inducing DNA fragmentation. This protein has also been shown to be a component of a splicing-dependent multiprotein exon junction complex (EJC) that is deposited at splice junctions on mRNAs, as a consequence of pre-mRNA splicing. It may thus be involved in mRNA metabolism associated with splicing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
- 规格:10ul 质粒
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