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人 GRPR (NM_005314) cDNA克隆
人 GRPR (NM_005314) cDNA克隆
  • 商品货号:FC148383
  • 已售 7 件 | 评价 0 人次 | 关注度 285
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    • accession:NM_005314
    • 基因别名:GRPR
    • 基因描述:Homo sapiens gastrin-releasing peptide receptor (GRPR), mRNA.
    • 载体:现货载体
    • CDS区长度:1155
    • 翻译后氨基酸长度:384
    • 基因简介:Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene. [provided by RefSeq, Jul 2008]
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列