- accession:NM_014555
- 基因别名:TRPM5
- 基因描述:Homo sapiens transient receptor potential cation channel, subfamily M, member 5 (TRPM5), mRNA.
- 载体:现货载体
- CDS区长度:3498
- 翻译后氨基酸长度:1165
- 基因简介:This gene encodes a member of the transient receptor potential (TRP) protein family, which is a diverse group of proteins with structural features typical of ion channels. This protein plays an important role in taste transduction, and has characteristics of a calcium-activated, non-selective cation channel that carries Na+, K+, and Cs+ ions equally well, but not Ca(2+) ions. It is activated by lower concentrations of intracellular Ca(2+), and inhibited by higher concentrations. It is also a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. This gene is located within the Beckwith-Wiedemann syndrome critical region-1 on chromosome 11p15.5, and has been shown to be imprinted, with exclusive expression from the paternal allele. [provided by RefSeq, Oct 2010]
- 规格:10ul 质粒
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