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- accession：NM_013371
- 基因别名：IL19
- 基因描述：Homo sapiens interleukin 19 (IL19), transcript variant 2, mRNA.
- 载体：现货载体
- CDS区长度：534
- 翻译后氨基酸长度：177
- TranscriptVariant：This variant (2) lacks an exon from the 5' end and contains two alternate 5' exons, resulting in a downstream AUG start codon, as compared to variant 1. The resulting isoform (2) has a shorter N-terminus, as compared to isoform 1.
- 基因简介：The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
