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人 ACACA (NM_198836) cDNA克隆
人 ACACA (NM_198836) cDNA克隆
  • 商品货号:FC150282
  • 已售 2 件 | 评价 0 人次 | 关注度 280
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    • accession:NM_198836
    • 基因别名:ACACA
    • 基因描述:Homo sapiens acetyl-CoA carboxylase alpha (ACACA), transcript variant 3, mRNA.
    • 载体:现货载体
    • CDS区长度:7041
    • 翻译后氨基酸长度:2346
    • TranscriptVariant:This variant (3) has an alternate 5' UTR exon, and uses a downstream start codon, as compared to variant (1). The resulting isoform (2) has a shorter N-terminus, as compared to isoform 1.
    • 基因简介:Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列