- accession:NM_015844
- 基因别名:MBD1
- 基因描述:Homo sapiens methyl-CpG binding domain protein 1 (MBD1), transcript variant 3, mRNA.
- 载体:现货载体
- CDS区长度:1650
- 翻译后氨基酸长度:549
- TranscriptVariant:This variant (3) lacks an in-frame coding exon compared to variant 1, resulting in a shorter isoform (3) missing an internal protein segment compared to isoform 1.
- 基因简介:The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains multiple domains: MBD at the N-terminus that functions both in binding to methylated DNA and in protein interactions; several CXXC-type zinc finger domains that mediate binding to non-methylated CpG dinucleotides; transcriptional repression domain (TRD) at the C-terminus that is involved in transcription repression and in protein interactions. Numerous alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Feb 2011]
- 规格:10ul 质粒
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