- 商品货号:F116236
- accession:NM_147188
- 基因别名:FBXO22
- 基因描述:Homo sapiens F-box protein 22 (FBXO22), transcript variant 1, mRNA.
- 载体: 现货载体
- CDS区长度:1212
- 翻译后氨基酸长度:403
- TranscriptVariant:This variant (1) represents the longest transcript and encodes the longer isoform (a).
- 基因简介:This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and, as a transcriptional target of the tumor protein p53, is thought to be involved in degradation of specific proteins in response to p53 induction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]
- 载体信息:自有图片地址
- 规格:10ul 质粒
CDS区参考序列: 点击查看序列翻译后氨基酸参数序列: 点击查看序列