• 商品货号：A12694

• 名称：Pacritinib (SB1518)
• 简介：Pacritinib, also known as SB1518, is an orally bioavailable inhibitor of Janus kinase 2 (JAK2) and the JAK2 mutant JAK2V617F with potential antineoplastic activity. Pacritinib competes with JAK2 for ATP binding, which may result in inhibition of JAK2 activation, inhibition of the JAK-STAT signaling pathway, and so caspase-dependent apoptosis.
• CASNO：937272-79-2
• 分子式：C28H32N4O3
• 分子量：472.58
• SMILES：C1CCN(C1)CCOC2=C3COC/C=C/COCC4=CC=CC(=C4)C5=NC(=NC=C5)NC(=C3)C=C2
• 保持条件：at -20°C 3 years Powder
• 同名：SB-1518; SB 1518
• 纯度：>98%
• 应用：JAK2/FLT3 inhibitor
• 作用机制：Inhibitor