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SB265610
SB265610
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  • 商品货号:A14195
  • 名称:SB265610
  • 简介:SB 265610 is a nonpeptide, allosteric, inverse agonist of CXCR2 (Kd = 2.51 nM) that prevents receptor activation by binding to a region distinct from the agonist binding site. It does not bind to the related CXCR1 receptor.1 It has been shown to prevent neutrophil chemotaxis both in vitro and in a rat model of hyperoxia-induced lung injury.
  • CASNO:211096-49-0
  • 分子式:C14H9BrN6O
  • 分子量:357.16
  • SMILES:C1=CC=C(C(=C1)NC(=O)NC2=CC=C(C3=NNN=C23)C#N)Br
  • 保持条件:at -20°C 3 years Powder
  • 同名:SB 265610,SB-265610
  • 纯度:>98%
  • 应用:CXCR2 antagonist
  • 作用机制:Antagonist