- accession:NM_198407
- 基因别名:GHSR
- 基因描述:Homo sapiens growth hormone secretagogue receptor (GHSR), transcript variant 1a, mRNA.
- 载体: 现货载体
- CDS区长度:1101
- 翻译后氨基酸长度:366
- TranscriptVariant:This variant (1a), also known as GHS-R1a, represents the completely spliced transcript, and encodes the longer isoform (1a). This transcript has been shown to encode a functional protein.
- 基因简介:This gene encodes a member of the G-protein coupled receptor family. The encoded protein may play a role in energy homeostasis and regulation of body weight. Two identified transcript variants are expressed in several tissues and are evolutionary conserved in fish and swine. One transcript, 1a, excises an intron and encodes the functional protein; this protein is the receptor for the Ghrelin ligand and defines a neuroendocrine pathway for growth hormone release. The second transcript (1b) retains the intron and does not function as a receptor for Ghrelin; however, it may function to attenuate activity of isoform 1a. Mutations in this gene are associated with autosomal idiopathic short stature.[provided by RefSeq, Apr 2010]
- 载体信息:自有图片地址
- 规格:10ul 质粒
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