- 商品货号:F136312
- accession:NM_145007
- 基因别名:NLRP11
- 基因描述:Homo sapiens NLR family, pyrin domain containing 11 (NLRP11), mRNA.
- 载体:现货载体
- CDS区长度:3102
- 翻译后氨基酸长度:1033
- 基因简介:NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP11, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM, Mar 2008]
- 载体信息:自有图片地址
- 规格:10ul 质粒
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