• accession：NM_001077238
• 基因别名：SPPL2B
• 基因描述：Homo sapiens signal peptide peptidase like 2B (SPPL2B), transcript variant 3, mRNA.
• 载体：现货载体
• CDS区长度：1536
• 翻译后氨基酸长度：511
• TranscriptVariant：This variant (3) uses an alternate splice site in the 3' coding region, compared to variant 2, resulting in an early stop codon. The encoded isoform (3) is shorter and has a distinct C-terminus compared to isoform 2.
• 基因简介：This gene encodes a member of the GXGD family of aspartic proteases. The GXGD proteases are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions. This enzyme localizes to endosomes, lysosomes, and the plasma membrane. It cleaves the transmembrane domain of tumor necrosis factor alpha to release the intracellular domain, which triggers cytokine expression in the innate and adaptive immunity pathways. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
• 载体信息：自有图片地址
• 规格：10ul 质粒

CDS区参考序列： 点击查看序列

ATGGCGGCAGCGGTGGCGGCTGCGCTGGCGCGGCTTTTGGCGGCCTTTCTGCTCCTCGCGGCCCAGGTGGCCTGTGAGTACGGCATGGTGCACGTGGTCTCCCAGGCCGGGGGCCCCGAAGGCAAAGACTACTGCATCCTCTACAACCCGCAGTGGGCCCATCTTCCGCACGACCTCAGCAAGGCATCTTTCCTGCAGCTGCGCAACTGGACGGCCTCCCTGCTCTGCTCCGCAGCCGACCTCCCCGCCCGTGGCTTCAGCAACCAGATCCCGCTGGTGGCGCGGGGGAACTGCACCTTCTATGAGAAAGTGAGGCTGGCCCAGGGCAGCGGAGCACGCGGGCTGCTCATCGTCAGCAGGGAGAGGCTGGTCCCCCCGGGGGGTAATAAGACGCAGTATGATGAGATTGGCATTCCCGTGGCCCTGCTCAGCTACAAAGACATGCTGGACATCTTCACGCGTTTCGGCCGCACGGTGAGGGCGGCGCTGTATGCGCCTAAGGAGCCGGTGCTGGACTACAACATGGTCATCATCTTCATCATGGCTGTGGGCACCGTCGCCATCGGCGGCTACTGGGCCGGGAGTCGGGACGTGAAGAAAAGGTACATGAAGCACAAGCGCGACGATGGGCCCGAGAAGCAGGAGGACGAGGCGGTGGACGTGACGCCGGTGATGACCTGCGTGTTTGTGGTGATGTGCTGCTCCATGCTGGTGCTGCTCTACTATTTCTACGATCTCCTCGTGTACGTGGTCATCGGGATCTTCTGCCTGGCCTCCGCCACCGGCCTCTACAGCTGCCTGGCGCCCTGTGTGCGGCGGCTGCCCTTCGGCAAGTGCAGGATCCCCAACAACAGCCTGCCCTACTTCCACAAGCGCCCGCAGGCCCGTATGCTGCTCCTGGCGCTCTTCTGCGTGGCCGTCAGCGTGGTGTGGGGCGTCTTCCGCAACGAGGACCAGTGGGCCTGGGTCCTCCAGGATGCCCTGGGCATCGCCTTCTGCCTCTACATGCTGAAGACCATCCGTCTGCCCACCTTCAAGGCCTGCACGCTGCTGCTGCTGGTGCTGTTCCTCTACGACATCTTCTTCGTGTTCATCACGCCCTTCCTGACCAAGAGTGGGAGCAGCATCATGGTGGAGGTGGCCACTGGGCCCTCGGACTCAGCCACCCGTGAGAAGCTGCCCATGGTCCTGAAGGTGCCCAGGCTGAACTCCTCACCTCTGGCCCTGTGTGACCGGCCCTTCTCCCTCCTGGGTTTCGGAGACATTTTGGTGCCAGGGCTGCTGGTGGCCTACTGCCACAGGTTTGACATCCAGGTACAGTCCTCCAGGGTATACTTCGTGGCCTGCACCATCGCCTATGGCGTTGGCCTCCTTGTGACATTCGTGGCACTGGCCCTGATGCAGCGTGGCCAGCCCGCTCTCCTCTACCTGGTGCCCTGCACGCTGGTGACGAGCTGCGCTGTGGCGCTCTGGCGCCGGGAGCTGGGCGTGTTCTGGACGGGCAGCGGCTTTGCGGTGAATACCAGTTTGCTCTGA

翻译后氨基酸参数序列： 点击查看序列

ATGGCGGCAGCGGTGGCGGCTGCGCTGGCGCGGCTTTTGGCGGCCTTTCTGCTCCTCGCGGCCCAGGTGGCCTGTGAGTACGGCATGGTGCACGTGGTCTCCCAGGCCGGGGGCCCCGAAGGCAAAGACTACTGCATCCTCTACAACCCGCAGTGGGCCCATCTTCCGCACGACCTCAGCAAGGCATCTTTCCTGCAGCTGCGCAACTGGACGGCCTCCCTGCTCTGCTCCGCAGCCGACCTCCCCGCCCGTGGCTTCAGCAACCAGATCCCGCTGGTGGCGCGGGGGAACTGCACCTTCTATGAGAAAGTGAGGCTGGCCCAGGGCAGCGGAGCACGCGGGCTGCTCATCGTCAGCAGGGAGAGGCTGGTCCCCCCGGGGGGTAATAAGACGCAGTATGATGAGATTGGCATTCCCGTGGCCCTGCTCAGCTACAAAGACATGCTGGACATCTTCACGCGTTTCGGCCGCACGGTGAGGGCGGCGCTGTATGCGCCTAAGGAGCCGGTGCTGGACTACAACATGGTCATCATCTTCATCATGGCTGTGGGCACCGTCGCCATCGGCGGCTACTGGGCCGGGAGTCGGGACGTGAAGAAAAGGTACATGAAGCACAAGCGCGACGATGGGCCCGAGAAGCAGGAGGACGAGGCGGTGGACGTGACGCCGGTGATGACCTGCGTGTTTGTGGTGATGTGCTGCTCCATGCTGGTGCTGCTCTACTATTTCTACGATCTCCTCGTGTACGTGGTCATCGGGATCTTCTGCCTGGCCTCCGCCACCGGCCTCTACAGCTGCCTGGCGCCCTGTGTGCGGCGGCTGCCCTTCGGCAAGTGCAGGATCCCCAACAACAGCCTGCCCTACTTCCACAAGCGCCCGCAGGCCCGTATGCTGCTCCTGGCGCTCTTCTGCGTGGCCGTCAGCGTGGTGTGGGGCGTCTTCCGCAACGAGGACCAGTGGGCCTGGGTCCTCCAGGATGCCCTGGGCATCGCCTTCTGCCTCTACATGCTGAAGACCATCCGTCTGCCCACCTTCAAGGCCTGCACGCTGCTGCTGCTGGTGCTGTTCCTCTACGACATCTTCTTCGTGTTCATCACGCCCTTCCTGACCAAGAGTGGGAGCAGCATCATGGTGGAGGTGGCCACTGGGCCCTCGGACTCAGCCACCCGTGAGAAGCTGCCCATGGTCCTGAAGGTGCCCAGGCTGAACTCCTCACCTCTGGCCCTGTGTGACCGGCCCTTCTCCCTCCTGGGTTTCGGAGACATTTTGGTGCCAGGGCTGCTGGTGGCCTACTGCCACAGGTTTGACATCCAGGTACAGTCCTCCAGGGTATACTTCGTGGCCTGCACCATCGCCTATGGCGTTGGCCTCCTTGTGACATTCGTGGCACTGGCCCTGATGCAGCGTGGCCAGCCCGCTCTCCTCTACCTGGTGCCCTGCACGCTGGTGACGAGCTGCGCTGTGGCGCTCTGGCGCCGGGAGCTGGGCGTGTTCTGGACGGGCAGCGGCTTTGCGGTGAATACCAGTTTGCTCTGA