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人WNT1(NM_005430)ORF克隆
人WNT1(NM_005430)ORF克隆
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  • 商品货号:F163982
  • accession:NM_005430
  • 基因别名:WNT1
  • 基因描述:Homo sapiens wingless-type MMTV integration site family, member 1 (WNT1), mRNA.
  • 载体:现货载体
  • CDS区长度:1113
  • 翻译后氨基酸长度:370
  • 基因简介:The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region. [provided by RefSeq, Jul 2008]
  • 载体信息:自有图片地址
  • 规格:10ul 质粒
CDS区参考序列: 点击查看序列
翻译后氨基酸参数序列: 点击查看序列