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- accession：NM_006420
- 基因别名：BIG2; PVNH2; dJ1164I10.1
- 基因描述：Homo sapiens ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) (ARFGEF2), mRNA.
- 载体：现货载体
- CDS区长度：5358
- 翻译后氨基酸长度：1785
- 基因简介：ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine-nucleotide exchange activity and also brefeldin A inhibition. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列ATGCAGGAGAGCCAGACCAAGAGCATGTTCGTGTCCCGGGCCCTGGAGAAGATCCTAGCCGACAAGGAGG
TGAAGCGGCCCCAGCACTCCCAGCTGCGCAGGGCCTGCCAGGTGGCGCTCGATGAAATTAAAGCAGAAAT
AGAAAAGCAGAGGCTTGGCACTGCTGCACCACCAAAGGCAAACTTCATTGAAGCTGACAAGTATTTTCTT
CCATTCGAGCTAGCTTGCCAGTCCAAGTCCCCAAGGGTAGTCAGCACATCCCTTGACTGCTTGCAGAAAC
TCATCGCATACGGGCACATCACTGGCAACGCCCCTGACAGTGGAGCCCCTGGGAAGCGGCTGATCGACAG
AATTGTTGAAACCATTTGCAGTTGTTTTCAGGGCCCTCAGACTGATGAAGGGGTTCAGTTACAAATAATT
AAGGCTCTTCTGACTGCAGTGACTTCCCCACACATTGAAATTCATGAGGGTACTATCCTGCAGACAGTGA
GAACATGTTACAATATCTATTTGGCCAGCAAAAATCTCATCAATCAAACCACTGCCAAGGCTACCCTTAC
TCAGATGCTGAACGTCATTTTCACCCGCATGGAAAACCAAGTGTTGCAGGAGGCCAGAGAACTGGAAAAA
CCAATCCAGTCAAAACCCCAGTCCCCTGTGATCCAAGCTGCAGCAGTATCCCCAAAGTTCGTTCGTTTGA
AGCACAGTCAGGCACAAAGCAAACCAACAACTCCCGAAAAAACAGATTTAACCAACGGTGAACATGCCAG
GAGTGATTCTGGAAAAGTAAGCACAGAAAATGGAGACGCACCCAGAGAAAGAGGCTCATCACTGTCAGGG
ACTGATGACGGAGCCCAGGAGGTGGTGAAGGACATCTTGGAAGATGTAGTCACATCTGCCATTAAAGAAG
CAGCGGAAAAGCATGGTCTGACAGAACCTGAGAGAGTTCTAGGTGAACTGGAGTGCCAGGAATGTGCTAT
TCCCCCAGGAGTTGATGAAAACTCACAGACCAACGGGATAGCCGATGACAGGCAGTCCTTGTCGTCAGCA
GATAATCTGGAATCGGATGCACAAGGACATCAAGTGGCTGCCAGGTTCTCCCACGTTCTGCAGAAGGATG
CCTTCCTTGTGTTCCGCTCCCTGTGCAAGCTGTCCATGAAACCCCTTGGTGAAGGCCCTCCAGACCCAAA
ATCCCATGAGCTGCGTTCCAAGGTGGTTTCCCTGCAGCTGCTCCTCTCTGTGTTGCAAAATGCTGGCCCC
GTATTCAGGACTCACGAGATGTTCATCAATGCAATCAAGCAATATCTCTGTGTGGCCTTGTCCAAAAACG
GCGTCTCTTCAGTGCCTGATGTCTTTGAGCTCTCTCTTGCCATTTTTCTTACTCTTCTTTCAAACTTTAA
AATGCACTTGAAAATGCAGATAGAGGTCTTTTTCAAAGAGATTTTCCTGAACATTTTAGAAACATCAACA
AGTTCTTTTGAGCACAGGTGGATGGTCATTCAGACTCTGACGAGGATCTGTGCAGATGCCCAGTGTGTTG
TGGATATTTATGTCAACTACGACTGTGATTTAAATGCTGCTAACATTTTTGAGCGCCTTGTAAATGATTT
ATCCAAAATTGCTCAGGGAAGAAGTGGACATGAGCTGGGAATGACACCTCTGCAGGAGCTCAGCCTGAGG
AAGAAAGGCCTGGAGTGCCTCGTGTCCATTCTCAAGTGCATGGTGGAGTGGAGCAAAGACCTGTATGTGA
ATCCCAACCACCAGACCAGCCTCGGTCAGGAGAGGCTCACGGATCAGGAAATAGGGGATGGGAAAGGCCT
TGACATGGCAAGACGGTGTAGTGTGACGTCCATGGAGTCCACAGTGTCCTCGGGGACCCAGACAACTGTT
CAGGATGACCCTGAGCAATTTGAGGTCATCAAGCAACAAAAAGAAATCATTGAACACGGCATCGAGCTGT
TCAACAAGAAACCCAAGAGGGGGATCCAGTTTCTCCAGGAGCAGGGCATGCTGGGAACGTCAGTTGAAGA
CATAGCCCAATTCCTGCACCAGGAGGAGCGCCTGGATTCCACCCAAGTAGGCGATTTTCTGGGAGATAGC
GCAAGGTTCAACAAGGAGGTGATGTATGCCTACGTGGACCAACTTGACTTCTGTGAAAAAGAATTTGTCT
CAGCCCTGCGGACATTCCTAGAAGGTTTCCGCCTACCTGGAGAAGCCCAAAAGATTGACCGATTAATGGA
GAAGTTTGCCGCAAGATACATAGAATGCAACCAAGGGCAAACTCTGTTTGCTAGTGCTGACACTGCTTAT
GTCCTAGCGTATTCAATTATTATGCTGACTACAGACTTGCACAGTCCTCAGGTAAAAAATAAAATGACGA
AAGAGCAGTATATTAAAATGAATCGGGGTATCAATGATAGTAAAGATCTGCCAGAAGAGTATCTCTCAAG
CATCTATGAAGAGATAGAAGGCAAGAAAATTGCAATGAAAGAAACAAAAGAGCTAACGATTGCAACCAAA
TCTACTAAGCAGAATGTAGCTAGTGAAAAGCAGCGGCGGCTGCTGTACAACTTAGAGATGGAGCAAATGG
CTAAAACAGCCAAAGCTCTGATGGAGGCTGTGAGCCATGCCAAAGCCCCGTTTACCAGTGCCACTCACCT
GGACCATGTCCGGCCAATGTTCAAACTGGTGTGGACGCCACTATTGGCAGCCTACAGCATCGGACTCCAG
AACTGTGATGACACTGAAGTGGCCTCCTTGTGTTTGGAAGGCATCCGATGTGCAATCCGAATCGCCTGCA
TCTTTGGAATGCAGCTGGAACGAGATGCCTATGTTCAGGCTCTTGCTCGCTTCTCCCTACTCACAGCCAG
CTCCAGCATCACAGAAATGAAGCAGAAAAACATCGACACCATTAAGACGCTTATCACAGTGGCTCACACC
GATGGCAACTACCTTGGGAATTCCTGGCATGAGATCTTGAAATGCATCAGCCAGCTGGAGCTCGCTCAGC
TGATAGGAACCGGTGTGAAGACGCGCTACCTGTCTGGATCTGGGCGTGAAAGAGAAGGGAGCCTGAAGGG
CCACACATTGGCAGGAGAAGAGTTCATGGGCCTTGGCCTCGGTAATTTGGTGAGTGGCGGAGTGGATAAA
AGACAGATGGCCAGCTTCCAAGAATCGGTTGGTGAGACCAGCTCGCAGAGTGTGGTTGTAGCTGTGGACA
GGATTTTTACTGGGTCTACCAGACTGGATGGAAATGCAATAGTTGACTTTGTCCGCTGGCTGTGTGCTGT
GTCCATGGATGAACTGGCTTCCCCCCACCATCCTCGCATGTTCAGCTTGCAGAAGATTGTGGAGATATCA
TACTACAACATGAATCGGATCCGACTACAGTGGTCTCGAATATGGCATGTGATTGGAGATCACTTCAATA
AGGTTGGCTGCAACCCTAATGAAGATGTGGCTATCTTTGCTGTTGACTCATTAAGGCAACTCTCCATGAA
GTTTCTTGAGAAGGGTGAATTAGCCAACTTCCGTTTCCAGAAAGATTTTCTGAGGCCCTTTGAGCATATT
ATGAAGAAAAACAGGTCTCCCACCATCCGGGACATGGCGATCCGCTGCATTGCCCAGATGGTGAACTCCC
AGGCGGCCAACATCCGCTCAGGTTGGAAGAACATCTTTGCCGTGTTCCACCAGGCAGCCTCTGATCATGA
TGGGAACATTGTGGAGCTGGCCTTCCAGACCACTTGCCACATTGTCACAACTATTTTCCAGCACCATTTT
CCTGCAGCCATCGATTCCTTTCAGGATGCTGTGAAGTGCTTATCAGAGTTCGCCTGCAACGCCGCTTTCC
CTGACACGAGCATGGAAGCGATTCGGCTCATCCGCTTCTGTGGCAAATACGTCTCTGAGAGGCCTCGGGT
GCTACAAGAATACACAAGTGATGACATGAATGTAGCTCCTGGTGACAGAGTCTGGGTCCGAGGCTGGTTC
CCCATCTTATTCGAACTCTCCTGCATCATTAATAGATGCAAGTTAGATGTACGAACAAGGGGACTCACAG
TCATGTTTGAGATCATGAAGAGCTATGGCCACACCTTTGAAAAGCACTGGTGGCAGGACCTGTTCAGAAT
CGTGTTTCGGATTTTTGACAATATGAAACTCCCTGAGCAACTGTCAGAGAAATCTGAGTGGATGACAACA
ACCTGCAATCACGCACTTTATGCTATTTGTGATGTTTTTACCCAGTTTTATGAAGCTTTGAATGAAGTTC
TTCTTTCTGATGTATTTGCACAATTGCAGTGGTGTGTCAAACAAGATAATGAACAGTTGGCGCGATCAGG
TACAAATTGCTTAGAAAACTTAGTAATATCCAATGGAGAGAAATTCAGTCCTGAAGTCTGGGATGAAACC
TGCAACTGTATGTTGGATATTTTCAAAACAACCATCCCACATGTTTTGCTGACATGGAGACCTGTAGGAA
TGGAGGAAGATTCATCAGAAAAGCATTTGGATGTGGATCTGGACCGCCAGTCTTTAAGCAGCATAGATAA
AAATCCCTCTGAGAGGGGACAGAGCCAGCTCTCTAACCCAACAGATGACAGCTGGAAGGGTAGACCATAC
GCAAATCAGAAACTGTTTGCCAGCCTCCTCATCAAGTGTGTGGTCCAGTTGGAATTGATACAGACCATTG
ACAACATTGTGTTCTACCCTGCGACGAGCAAAAAGGAGGATGCAGAGCACATGGTTGCCGCCCAGCAAGA
CACGCTGGATGCAGATATCCACATAGAGACGGAGGATCAGGGCATGTATAAGTACATGTCTTCCCAGCAC
CTCTTCAAGCTGTTGGACTGTTTGCAGGAATCCCATTCATTCTCAAAGGCCTTCAACTCCAATTACGAGC
AGCGGACTGTCCTGTGGCGAGCAGGTTTTAAGGGCAAGTCTAAACCCAATCTTCTAAAACAAGAAACCAG
CAGCCTGGCCTGTTGTTTGAGGATCCTGTTTCGAATGTATGTTGATGAGAACCGCAGGGATTCCTGGGAA
GAAATACAGCAGAGACTTTTAACTGTTTGCAGTGAAGCTCTTGCCTATTTCATCACTGTGAATTCTGAGA
GCCATCGGGAGGCCTGGACAAGTCTCTTGTTGTTACTTCTAACTAAAACCCTCAAAATAAATGATGAAAA
GTTCAAAGCACATGCTTCAATGTACTACCCCTACTTGTGTGAAATTATGCAGTTTGACCTGATCCCTGAG
CTCCGAGCAGTTCTGCGGAAGTTCTTCCTACGGATAGGTGTTGTGTATAAGATATGGATACCAGAAGAGC
CATCACAGGTACCAGCAGCACTGTCACCAGTGTGGTAG翻译后氨基酸参数序列： 点击查看序列ATGCAGGAGAGCCAGACCAAGAGCATGTTCGTGTCCCGGGCCCTGGAGAAGATCCTAGCCGACAAGGAGG
TGAAGCGGCCCCAGCACTCCCAGCTGCGCAGGGCCTGCCAGGTGGCGCTCGATGAAATTAAAGCAGAAAT
AGAAAAGCAGAGGCTTGGCACTGCTGCACCACCAAAGGCAAACTTCATTGAAGCTGACAAGTATTTTCTT
CCATTCGAGCTAGCTTGCCAGTCCAAGTCCCCAAGGGTAGTCAGCACATCCCTTGACTGCTTGCAGAAAC
TCATCGCATACGGGCACATCACTGGCAACGCCCCTGACAGTGGAGCCCCTGGGAAGCGGCTGATCGACAG
AATTGTTGAAACCATTTGCAGTTGTTTTCAGGGCCCTCAGACTGATGAAGGGGTTCAGTTACAAATAATT
AAGGCTCTTCTGACTGCAGTGACTTCCCCACACATTGAAATTCATGAGGGTACTATCCTGCAGACAGTGA
GAACATGTTACAATATCTATTTGGCCAGCAAAAATCTCATCAATCAAACCACTGCCAAGGCTACCCTTAC
TCAGATGCTGAACGTCATTTTCACCCGCATGGAAAACCAAGTGTTGCAGGAGGCCAGAGAACTGGAAAAA
CCAATCCAGTCAAAACCCCAGTCCCCTGTGATCCAAGCTGCAGCAGTATCCCCAAAGTTCGTTCGTTTGA
AGCACAGTCAGGCACAAAGCAAACCAACAACTCCCGAAAAAACAGATTTAACCAACGGTGAACATGCCAG
GAGTGATTCTGGAAAAGTAAGCACAGAAAATGGAGACGCACCCAGAGAAAGAGGCTCATCACTGTCAGGG
ACTGATGACGGAGCCCAGGAGGTGGTGAAGGACATCTTGGAAGATGTAGTCACATCTGCCATTAAAGAAG
CAGCGGAAAAGCATGGTCTGACAGAACCTGAGAGAGTTCTAGGTGAACTGGAGTGCCAGGAATGTGCTAT
TCCCCCAGGAGTTGATGAAAACTCACAGACCAACGGGATAGCCGATGACAGGCAGTCCTTGTCGTCAGCA
GATAATCTGGAATCGGATGCACAAGGACATCAAGTGGCTGCCAGGTTCTCCCACGTTCTGCAGAAGGATG
CCTTCCTTGTGTTCCGCTCCCTGTGCAAGCTGTCCATGAAACCCCTTGGTGAAGGCCCTCCAGACCCAAA
ATCCCATGAGCTGCGTTCCAAGGTGGTTTCCCTGCAGCTGCTCCTCTCTGTGTTGCAAAATGCTGGCCCC
GTATTCAGGACTCACGAGATGTTCATCAATGCAATCAAGCAATATCTCTGTGTGGCCTTGTCCAAAAACG
GCGTCTCTTCAGTGCCTGATGTCTTTGAGCTCTCTCTTGCCATTTTTCTTACTCTTCTTTCAAACTTTAA
AATGCACTTGAAAATGCAGATAGAGGTCTTTTTCAAAGAGATTTTCCTGAACATTTTAGAAACATCAACA
AGTTCTTTTGAGCACAGGTGGATGGTCATTCAGACTCTGACGAGGATCTGTGCAGATGCCCAGTGTGTTG
TGGATATTTATGTCAACTACGACTGTGATTTAAATGCTGCTAACATTTTTGAGCGCCTTGTAAATGATTT
ATCCAAAATTGCTCAGGGAAGAAGTGGACATGAGCTGGGAATGACACCTCTGCAGGAGCTCAGCCTGAGG
AAGAAAGGCCTGGAGTGCCTCGTGTCCATTCTCAAGTGCATGGTGGAGTGGAGCAAAGACCTGTATGTGA
ATCCCAACCACCAGACCAGCCTCGGTCAGGAGAGGCTCACGGATCAGGAAATAGGGGATGGGAAAGGCCT
TGACATGGCAAGACGGTGTAGTGTGACGTCCATGGAGTCCACAGTGTCCTCGGGGACCCAGACAACTGTT
CAGGATGACCCTGAGCAATTTGAGGTCATCAAGCAACAAAAAGAAATCATTGAACACGGCATCGAGCTGT
TCAACAAGAAACCCAAGAGGGGGATCCAGTTTCTCCAGGAGCAGGGCATGCTGGGAACGTCAGTTGAAGA
CATAGCCCAATTCCTGCACCAGGAGGAGCGCCTGGATTCCACCCAAGTAGGCGATTTTCTGGGAGATAGC
GCAAGGTTCAACAAGGAGGTGATGTATGCCTACGTGGACCAACTTGACTTCTGTGAAAAAGAATTTGTCT
CAGCCCTGCGGACATTCCTAGAAGGTTTCCGCCTACCTGGAGAAGCCCAAAAGATTGACCGATTAATGGA
GAAGTTTGCCGCAAGATACATAGAATGCAACCAAGGGCAAACTCTGTTTGCTAGTGCTGACACTGCTTAT
GTCCTAGCGTATTCAATTATTATGCTGACTACAGACTTGCACAGTCCTCAGGTAAAAAATAAAATGACGA
AAGAGCAGTATATTAAAATGAATCGGGGTATCAATGATAGTAAAGATCTGCCAGAAGAGTATCTCTCAAG
CATCTATGAAGAGATAGAAGGCAAGAAAATTGCAATGAAAGAAACAAAAGAGCTAACGATTGCAACCAAA
TCTACTAAGCAGAATGTAGCTAGTGAAAAGCAGCGGCGGCTGCTGTACAACTTAGAGATGGAGCAAATGG
CTAAAACAGCCAAAGCTCTGATGGAGGCTGTGAGCCATGCCAAAGCCCCGTTTACCAGTGCCACTCACCT
GGACCATGTCCGGCCAATGTTCAAACTGGTGTGGACGCCACTATTGGCAGCCTACAGCATCGGACTCCAG
AACTGTGATGACACTGAAGTGGCCTCCTTGTGTTTGGAAGGCATCCGATGTGCAATCCGAATCGCCTGCA
TCTTTGGAATGCAGCTGGAACGAGATGCCTATGTTCAGGCTCTTGCTCGCTTCTCCCTACTCACAGCCAG
CTCCAGCATCACAGAAATGAAGCAGAAAAACATCGACACCATTAAGACGCTTATCACAGTGGCTCACACC
GATGGCAACTACCTTGGGAATTCCTGGCATGAGATCTTGAAATGCATCAGCCAGCTGGAGCTCGCTCAGC
TGATAGGAACCGGTGTGAAGACGCGCTACCTGTCTGGATCTGGGCGTGAAAGAGAAGGGAGCCTGAAGGG
CCACACATTGGCAGGAGAAGAGTTCATGGGCCTTGGCCTCGGTAATTTGGTGAGTGGCGGAGTGGATAAA
AGACAGATGGCCAGCTTCCAAGAATCGGTTGGTGAGACCAGCTCGCAGAGTGTGGTTGTAGCTGTGGACA
GGATTTTTACTGGGTCTACCAGACTGGATGGAAATGCAATAGTTGACTTTGTCCGCTGGCTGTGTGCTGT
GTCCATGGATGAACTGGCTTCCCCCCACCATCCTCGCATGTTCAGCTTGCAGAAGATTGTGGAGATATCA
TACTACAACATGAATCGGATCCGACTACAGTGGTCTCGAATATGGCATGTGATTGGAGATCACTTCAATA
AGGTTGGCTGCAACCCTAATGAAGATGTGGCTATCTTTGCTGTTGACTCATTAAGGCAACTCTCCATGAA
GTTTCTTGAGAAGGGTGAATTAGCCAACTTCCGTTTCCAGAAAGATTTTCTGAGGCCCTTTGAGCATATT
ATGAAGAAAAACAGGTCTCCCACCATCCGGGACATGGCGATCCGCTGCATTGCCCAGATGGTGAACTCCC
AGGCGGCCAACATCCGCTCAGGTTGGAAGAACATCTTTGCCGTGTTCCACCAGGCAGCCTCTGATCATGA
TGGGAACATTGTGGAGCTGGCCTTCCAGACCACTTGCCACATTGTCACAACTATTTTCCAGCACCATTTT
CCTGCAGCCATCGATTCCTTTCAGGATGCTGTGAAGTGCTTATCAGAGTTCGCCTGCAACGCCGCTTTCC
CTGACACGAGCATGGAAGCGATTCGGCTCATCCGCTTCTGTGGCAAATACGTCTCTGAGAGGCCTCGGGT
GCTACAAGAATACACAAGTGATGACATGAATGTAGCTCCTGGTGACAGAGTCTGGGTCCGAGGCTGGTTC
CCCATCTTATTCGAACTCTCCTGCATCATTAATAGATGCAAGTTAGATGTACGAACAAGGGGACTCACAG
TCATGTTTGAGATCATGAAGAGCTATGGCCACACCTTTGAAAAGCACTGGTGGCAGGACCTGTTCAGAAT
CGTGTTTCGGATTTTTGACAATATGAAACTCCCTGAGCAACTGTCAGAGAAATCTGAGTGGATGACAACA
ACCTGCAATCACGCACTTTATGCTATTTGTGATGTTTTTACCCAGTTTTATGAAGCTTTGAATGAAGTTC
TTCTTTCTGATGTATTTGCACAATTGCAGTGGTGTGTCAAACAAGATAATGAACAGTTGGCGCGATCAGG
TACAAATTGCTTAGAAAACTTAGTAATATCCAATGGAGAGAAATTCAGTCCTGAAGTCTGGGATGAAACC
TGCAACTGTATGTTGGATATTTTCAAAACAACCATCCCACATGTTTTGCTGACATGGAGACCTGTAGGAA
TGGAGGAAGATTCATCAGAAAAGCATTTGGATGTGGATCTGGACCGCCAGTCTTTAAGCAGCATAGATAA
AAATCCCTCTGAGAGGGGACAGAGCCAGCTCTCTAACCCAACAGATGACAGCTGGAAGGGTAGACCATAC
GCAAATCAGAAACTGTTTGCCAGCCTCCTCATCAAGTGTGTGGTCCAGTTGGAATTGATACAGACCATTG
ACAACATTGTGTTCTACCCTGCGACGAGCAAAAAGGAGGATGCAGAGCACATGGTTGCCGCCCAGCAAGA
CACGCTGGATGCAGATATCCACATAGAGACGGAGGATCAGGGCATGTATAAGTACATGTCTTCCCAGCAC
CTCTTCAAGCTGTTGGACTGTTTGCAGGAATCCCATTCATTCTCAAAGGCCTTCAACTCCAATTACGAGC
AGCGGACTGTCCTGTGGCGAGCAGGTTTTAAGGGCAAGTCTAAACCCAATCTTCTAAAACAAGAAACCAG
CAGCCTGGCCTGTTGTTTGAGGATCCTGTTTCGAATGTATGTTGATGAGAACCGCAGGGATTCCTGGGAA
GAAATACAGCAGAGACTTTTAACTGTTTGCAGTGAAGCTCTTGCCTATTTCATCACTGTGAATTCTGAGA
GCCATCGGGAGGCCTGGACAAGTCTCTTGTTGTTACTTCTAACTAAAACCCTCAAAATAAATGATGAAAA
GTTCAAAGCACATGCTTCAATGTACTACCCCTACTTGTGTGAAATTATGCAGTTTGACCTGATCCCTGAG
CTCCGAGCAGTTCTGCGGAAGTTCTTCCTACGGATAGGTGTTGTGTATAAGATATGGATACCAGAAGAGC
CATCACAGGTACCAGCAGCACTGTCACCAGTGTGGTAG
