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- accession：NM_057090
- 基因别名：EVN; NBN; ENOVIN
- 基因描述：Homo sapiens artemin (ARTN), transcript variant 4, mRNA.
- 载体：现货载体
- CDS区长度：687
- 翻译后氨基酸长度：228
- TranscriptVariant：This variant (4) uses an alternate in-frame splice site in the coding region, compared to variant 2. The resulting isoform (3) is longer than isoform 1. Variants 4 and 5 encode the same isoform (3).
- 基因简介：The protein encoded by this gene is a member of the glial cell line-derived neurotophic factor (GDNF) family of ligands which are a group of ligands within the TGF-beta superfamily of signaling molecules. GDNFs are unique in having neurotrophic properties and have potential use for gene therapy in neurodegenerative disease. Artemin has been shown in culture to support the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. Its role in the PNS and CNS is further substantiated by its expression pattern in the proximity of these neurons. This protein is a ligand for the RET receptor and uses GFR-alpha 3 as a coreceptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
