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- accession：NM_001025160
- 基因别名：TM7LN1
- 基因描述：Homo sapiens CD97 molecule (CD97), transcript variant 3, mRNA.
- 载体：现货载体
- CDS区长度：2361
- 翻译后氨基酸长度：786
- TranscriptVariant：This variant (3) lacks an exon in the coding region but maintains the reading frame, compared to variant 1. The encoded isoform (3, also known as CD97(EGF 1,2,3,5)) is shorter than isoform 1.
- 基因简介：This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19. [provided by RefSeq, Jun 2011]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
