- accession:NM_001042404
- 基因别名:KAB; FAM68A; KIAA0470
- 基因描述:Homo sapiens centrosomal protein 170kDa (CEP170), transcript variant beta, mRNA.
- 载体:现货载体
- CDS区长度:4461
- 翻译后氨基酸长度:1486
- TranscriptVariant:This variant (beta, also known as 2) lacks an alternate in-frame exon, compared to variant alpha, resulting in a shorter protein (isoform beta), compared to isoform alpha.
- 基因简介:The product of this gene is a component of the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. During interphase, the encoded protein localizes to the sub-distal appendages of mature centrioles, which are microtubule-based structures thought to help organize centrosomes. During mitosis, the protein associates with spindle microtubules near the centrosomes. The protein interacts with and is phosphorylated by polo-like kinase 1, and functions in maintaining microtubule organization and cell morphology. The human genome contains a putative transcribed pseudogene. Several alternatively spliced transcript variants of this gene have been found, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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