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- accession：NM_130445
- 基因别名：KS; KNO; KNO1
- 基因描述：Homo sapiens collagen, type XVIII, alpha 1 (COL18A1), transcript variant 2, mRNA.
- 载体：现货载体
- CDS区长度：4011
- 翻译后氨基酸长度：1336
- TranscriptVariant：This variant (2) is generated from a more distal promoter. It has an alternate 5' UTR and 5' CDS, as compared to variant 3. The resulting isoform (2) has a shorter and different N-terminus, as compared to isoform 3.
- 基因简介：This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. The proteolytically produced C-terminal fragment of type XVIII collagen is endostatin, a potent antiangiogenic protein. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
