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- accession：NM_004762
- 基因别名：B2-1; SEC7; PSCD1; D17S811E; CYTOHESIN-1
- 基因描述：Homo sapiens cytohesin 1 (CYTH1), transcript variant 1, mRNA.
- 载体：现货载体
- CDS区长度：1197
- 翻译后氨基酸长度：398
- TranscriptVariant：This variant (1) has an extra 3-base pair sequence in the region encoding the PH domain; the resulting protein isoform has an additional glycine residue.
- 基因简介：The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This gene is highly expressed in natural killer and peripheral T cells, and regulates the adhesiveness of integrins at the plasma membrane of lymphocytes. The encoded protein is 83% homologous to that of CYTH2. [provided by RefSeq, Aug 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
