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人 ESPL1 (NM_012291) cDNA克隆
人 ESPL1 (NM_012291) cDNA克隆
  • 商品货号:FC169842
  • 已售 4 件 | 评价 0 人次 | 关注度 483
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    • accession:NM_012291
    • 基因别名:ESP1; SEPA
    • 基因描述:Homo sapiens extra spindle pole bodies homolog 1 (S. cerevisiae) (ESPL1), mRNA.
    • 载体:现货载体
    • CDS区长度:6363
    • 翻译后氨基酸长度:2120
    • 基因简介:Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 (MIM 604358) or STAG2 (MIM 300826) in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 (RAD21; MIM 606462) by ESPL1, or separase, which initiates the final separation of sister chromatids (Sun et al., 2009 [PubMed 19345191]).[supplied by OMIM, Nov 2010]
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列