- accession:NM_001145546
- 基因描述:Homo sapiens galanin-like peptide (GALP), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:150
- 翻译后氨基酸长度:49
- TranscriptVariant:This variant (2) lacks an exon in the coding region, which results in a frameshift and an early stop codon compared to variant 1. The encoded isoform (2) has a distinct and shorter C-terminus compared to isoform 1. This variant, termed alarin, is a candidate for nonsense-mediated mRNA decay (NMD) but is being represented as protein-coding based on evidence supporting the transcript and protein described in PMID 16954604. The exon structure of this variant is based on Figure 1 from PMID 16954604.
- 基因简介:This gene encodes a member of the galanin family of neuropeptides. The encoded protein binds galanin receptors 1, 2 and 3 with the highest affinity for galanin receptor 3 and has been implicated in biological processes involving the central nervous system including hypothalamic regulation of metabolism and reproduction. A peptide encoded by a splice variant of this gene, termed alarin, may have vasoactive properties and serve as a marker for neuroblastic tumors.[provided by RefSeq, Mar 2009]
- 规格:10ul 质粒
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