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- accession：NM_003325
- 基因别名：TUP1; DGCR1; TUPLE1
- 基因描述：Homo sapiens histone cell cycle regulator (HIRA), mRNA.
- 载体：现货载体
- CDS区长度：3054
- 翻译后氨基酸长度：1017
- 基因简介：This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
