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人 LATS2 (NM_014572) cDNA克隆
人 LATS2 (NM_014572) cDNA克隆
  • 商品货号:FC171355
  • 已售 7 件 | 评价 0 人次 | 关注度 447
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    • accession:NM_014572
    • 基因别名:KPM
    • 基因描述:Homo sapiens large tumor suppressor kinase 2 (LATS2), mRNA.
    • 载体:现货载体
    • CDS区长度:3267
    • 翻译后氨基酸长度:1088
    • 基因简介:This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression. [provided by RefSeq, Jul 2008]
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列