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- accession：NM_001135610
- 基因别名：RIZ; KMT8; RIZ1; RIZ2; MTB-ZF; HUMHOXY1
- 基因描述：Homo sapiens PR domain containing 2, with ZNF domain (PRDM2), transcript variant 4, mRNA.
- 载体：现货载体
- CDS区长度：681
- 翻译后氨基酸长度：226
- TranscriptVariant：This variant (4) has an alternate 5' UTR and lacks two internal coding exons compared to variant 1. The resulting isoform (d) is much shorter and has a distinct C-terminus compared to isoform a.
- 基因简介：This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
