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人 RUNX2 (NM_001278478) cDNA克隆
人 RUNX2 (NM_001278478) cDNA克隆
  • 商品货号:FC168903
  • 已售 7 件 | 评价 0 人次 | 关注度 460
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    • accession:NM_001278478
    • 基因别名:CCD; AML3; CCD1; CLCD; OSF2; CBFA1; OSF-2; PEA2aA; PEBP2aA; CBF-alpha-1
    • 基因描述:Homo sapiens runt-related transcription factor 2 (RUNX2), transcript variant 4, mRNA.
    • 载体:现货载体
    • CDS区长度:1458
    • 翻译后氨基酸长度:485
    • TranscriptVariant:This variant (4) contains an alternate 5'-most exon, lacks an in-frame exon in the 3' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (d) has a distinct and shorter N-terminus, compared to isoform a.
    • 基因简介:This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing. [provided by RefSeq, Jul 2008]
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列