×
![]()
- accession：NM_133266
- 基因别名：SHANK; AUTS17; CORTBP1; CTTNBP1; ProSAP1; SPANK-3
- 基因描述：Homo sapiens SH3 and multiple ankyrin repeat domains 2 (SHANK2), transcript variant 2, mRNA.
- 载体：现货载体
- CDS区长度：3786
- 翻译后氨基酸长度：1261
- TranscriptVariant：This variant (2) represents use of a putative alternate promoter and 5' UTR, and uses an alternate start codon, compared to variant 1. The resulting isoform (2) has a substantially shorter and distinct N-terminus, compared to isoform 1.
- 基因简介：This gene encodes a protein that is a member of the Shank family of synaptic proteins that may function as molecular scaffolds in the postsynaptic density (PSD). Shank proteins contain multiple domains for protein-protein interaction, including ankyrin repeats, an SH3 domain, a PSD-95/Dlg/ZO-1 domain, a sterile alpha motif domain, and a proline-rich region. This particular family member contains a PDZ domain, a consensus sequence for cortactin SH3 domain-binding peptides and a sterile alpha motif. The alternative splicing demonstrated in Shank genes has been suggested as a mechanism for regulating the molecular structure of Shank and the spectrum of Shank-interacting proteins in the PSDs of adult and developing brain. Two alternative splice variants, encoding distinct isoforms, are reported. Additional splice variants exist but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
