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- accession：NM_005678
- 基因描述：Homo sapiens SNRPN upstream reading frame (SNURF), transcript variant 1, mRNA.
- 载体：现货载体
- CDS区长度：216
- 翻译后氨基酸长度：71
- TranscriptVariant：This variant (1) includes exons 1-10 in a bicistronic transcript that also contains a downstream open reading frame for the SNRPN gene. This longer transcript is the predominant form, although the monocistronic and bicistronic transcripts encode identical proteins, with alternate splicing occurring only in the 3' UTR.
- 基因简介：This gene encodes a highly basic protein localized to the nucleus. The evolutionarily constrained open reading frame is found on a bicistronic transcript which has a downstream ORF encoding the small nuclear ribonucleoprotein polypeptide N. The upstream coding region utilizes the first three exons of the transcript, a region that has been identified as an imprinting center. Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5' untranslated region but the full-length nature of these transcripts has not been determined. An alternate exon has been identified that substitutes for exon 4 and leads to a truncated, monocistronic transcript. Alternative splicing or deletion caused by a translocation event in the 5' UTR or coding region of this gene leads to Angelman syndrome or Prader-Willi syndrome due to parental imprint switch failure. The function of this protein is not yet known. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
