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- accession：NM_003745
- 基因别名：JAB; CIS1; SSI1; TIP3; CISH1; SSI-1; SOCS-1
- 基因描述：Homo sapiens suppressor of cytokine signaling 1 (SOCS1), mRNA.
- 载体：现货载体
- CDS区长度：636
- 翻译后氨基酸长度：211
- 基因简介：This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
