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人 SPEN (NM_015001) cDNA克隆
人 SPEN (NM_015001) cDNA克隆
  • 商品货号:FC171041
  • 已售 7 件 | 评价 0 人次 | 关注度 430
    • accession:NM_015001
    • 基因别名:MINT; SHARP; RBM15C; HIAA0929; RP1-134O19.1
    • 基因描述:Homo sapiens spen family transcriptional repressor (SPEN), mRNA.
    • 载体:现货载体
    • CDS区长度:10995
    • 翻译后氨基酸长度:3664
    • 基因简介:This gene encodes a hormone inducible transcriptional repressor. Repression of transcription by this gene product can occur through interactions with other repressors, by the recruitment of proteins involved in histone deacetylation, or through sequestration of transcriptional activators. The product of this gene contains a carboxy-terminal domain that permits binding to other corepressor proteins. This domain also permits interaction with members of the NuRD complex, a nucleosome remodeling protein complex that contains deacetylase activity. In addition, this repressor contains several RNA recognition motifs that confer binding to a steroid receptor RNA coactivator; this binding can modulate the activity of both liganded and nonliganded steroid receptors. [provided by RefSeq, Jul 2008]
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列