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- accession：NM_000459
- 基因别名：TIE2; VMCM; TIE-2; VMCM1; CD202B
- 基因描述：Homo sapiens TEK tyrosine kinase， endothelial (TEK)， mRNA.
- 载体：pLV3-CMV-hTEK(NM_000459)-3×FLAG-CopGFP-Puro
- CDS区长度：3375
- 翻译后氨基酸长度：1124
- 基因简介：The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice， rats， and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase. [provided by RefSeq， Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
