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人 TG (NM_003235) cDNA克隆
人 TG (NM_003235) cDNA克隆
  • 商品货号:FC163895
  • 已售 2 件 | 评价 0 人次 | 关注度 365
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    • accession:NM_003235
    • 基因别名:TGN; AITD3
    • 基因描述:Homo sapiens thyroglobulin (TG), mRNA.
    • 载体:现货载体
    • CDS区长度:8307
    • 翻译后氨基酸长度:2768
    • 基因简介:Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis. [provided by RefSeq, Nov 2009]
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列