- accession:NM_003235
- 基因别名:TGN; AITD3
- 基因描述:Homo sapiens thyroglobulin (TG), mRNA.
- 载体:现货载体
- CDS区长度:8307
- 翻译后氨基酸长度:2768
- 基因简介:Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis. [provided by RefSeq, Nov 2009]
- 规格:10ul 质粒
CDS区参考序列: 点击查看序列ATGGCCCTGGTCCTGGAGATCTTCACCCTGCTGGCCTCCATCTGCTGGGTGTCGGCCAATATCTTCGAGT
ACCAGGTGGATGCCCAGCCCCTTCGTCCCTGTGAGCTGCAGAGGGAAACGGCCTTTCTGAAGCAAGCAGA
CTACGTGCCCCAGTGTGCAGAGGATGGCAGCTTCCAGACTGTCCAGTGCCAGAACGACGGCCGCTCCTGC
TGGTGTGTGGGTGCCAACGGCAGTGAAGTGCTGGGCAGCAGGCAGCCAGGACGGCCTGTGGCTTGTCTGT
CATTTTGTCAGCTACAGAAACAGCAGATCTTACTGAGTGGCTACATTAACAGCACAGACACCTCCTACCT
CCCTCAGTGTCAGGATTCAGGGGACTACGCGCCTGTTCAGTGTGATGTGCAGCAGGTCCAGTGCTGGTGT
GTGGACGCAGAGGGGATGGAGGTGTATGGGACCCGCCAGCTGGGGAGGCCAAAGCGATGTCCAAGGAGCT
GTGAAATAAGAAATCGTCGTCTTCTCCACGGGGTGGGAGATAAGTCACCACCCCAGTGTTCTGCGGAGGG
AGAGTTTATGCCTGTCCAGTGCAAATTTGTCAACACCACAGACATGATGATTTTTGATCTGGTCCACAGC
TACAACAGGTTTCCAGATGCATTTGTGACCTTCAGTTCCTTCCAGAGGAGGTTCCCTGAGGTATCTGGGT
ATTGCCACTGTGCTGACAGCCAAGGGCGGGAACTGGCTGAGACAGGTTTGGAGTTGTTACTGGATGAAAT
TTATGACACCATTTTTGCTGGCCTGGACCTTCCTTCCACCTTCACTGAAACCACCCTGTACCGGATACTG
CAGAGACGGTTCCTCGCAGTTCAATCAGTCATCTCTGGCAGATTCCGATGCCCCACAAAATGTGAAGTGG
AGCGGTTTACAGCAACCAGCTTTGGTCACCCCTATGTTCCAAGCTGCCGCCGAAATGGCGACTATCAGGC
GGTGCAGTGCCAGACGGAAGGGCCCTGCTGGTGTGTGGACGCCCAGGGGAAGGAAATGCATGGAACCCGG
CAGCAAGGGGAGCCGCCATCTTGTGCTGAAGGCCAATCTTGTGCCTCCGAAAGGCAGCAGGCCTTGTCCA
GACTCTACTTTGGGACCTCAGGCTACTTCAGCCAGCACGACCTGTTCTCTTCCCCAGAGAAAAGATGGGC
CTCTCCAAGAGTAGCCAGATTTGCCACATCCTGCCCACCCACGATCAAGGAGCTCTTTGTGGACTCTGGG
CTTCTCCGCCCAATGGTGGAGGGACAGAGCCAACAGTTTTCTGTCTCAGAAAATCTTCTCAAAGAAGCCA
TCCGAGCAATTTTTCCCTCCCGAGGGCTGGCTCGTCTTGCCCTTCAGTTTACCACCAACCCAAAGAGACT
CCAGCAAAACCTTTTTGGAGGGAAATTTTTGGTGAATGTTGGCCAGTTTAACTTGTCTGGAGCCCTTGGC
ACAAGAGGCACATTTAACTTCAGTCAATTTTTCCAGCAACTTGGTCTTGCAAGCTTCTTGAATGGAGGGA
GACAAGAAGATTTGGCCAAGCCACTCTCTGTGGGATTAGATTCAAATTCTTCCACAGGAACCCCTGAAGC
TGCTAAGAAGGATGGTACTATGAATAAGCCAACTGTGGGCAGCTTTGGCTTTGAAATTAACCTACAAGAG
AACCAAAATGCCCTCAAATTCCTTGCTTCTCTCCTGGAGCTTCCAGAATTCCTTCTCTTCTTGCAACATG
CTATCTCTGTGCCAGAAGATGTGGCAAGAGATTTAGGTGATGTGATGGAAACGGTACTCAGCTCCCAGAC
CTGTGAGCAGACACCTGAAAGGCTATTTGTCCCATCATGCACGACAGAAGGAAGCTATGAGGATGTCCAA
TGCTTTTCCGGAGAGTGCTGGTGTGTGAATTCCTGGGGCAAAGAGCTTCCAGGCTCAAGAGTCAGAGGTG
GACAGCCAAGGTGCCCCACAGACTGTGAAAAGCAAAGGGCTCGCATGCAAAGCCTCATGGGCAGCCAGCC
TGCTGGCTCCACCTTGTTTGTCCCTGCTTGTACTAGTGAGGGACATTTCCTGCCTGTCCAGTGCTTCAAC
TCAGAGTGCTACTGTGTTGATGCTGAGGGTCAGGCCATTCCTGGAACTCGAAGTGCAATAGGGAAGCCCA
AGAAATGCCCCACGCCCTGTCAATTACAGTCTGAGCAAGCTTTCCTCAGGACGGTGCAGGCCCTGCTCTC
TAACTCCAGCATGCTACCCACCCTTTCCGACACCTACATCCCACAGTGCAGCACCGATGGGCAGTGGAGA
CAAGTGCAATGCAATGGGCCTCCTGAGCAGGTCTTCGAGTTGTACCAACGATGGGAGGCTCAGAACAAGG
GCCAGGATCTGACGCCTGCCAAGCTGCTAGTGAAGATCATGAGCTACAGAGAAGCAGCTTCCGGAAACTT
CAGTCTCTTTATTCAAAGTCTGTATGAGGCTGGCCAGCAAGATGTCTTCCCGGTGCTGTCACAATACCCT
TCTCTGCAAGATGTCCCACTAGCAGCACTGGAAGGGAAACGGCCCCAGCCCAGGGAGAATATCCTCCTGG
AGCCCTACCTCTTCTGGCAGATCTTAAATGGCCAACTCAGCCAATACCCGGGGTCCTACTCAGACTTCAG
CACTCCTTTGGCACATTTTGATCTTCGGAACTGCTGGTGTGTGGATGAGGCTGGCCAAGAACTGGAAGGA
ATGCGGTCTGAGCCAAGCAAGCTCCCAACATGTCCTGGCTCCTGTGAGGAAGCAAAGCTCCGTGTACTGC
AGTTCATTAGGGAAACGGAAGAGATTGTTTCAGCTTCCAACAGTTCTCGGTTCCCTCTGGGGGAGAGTTT
CCTGGTGGCCAAGGGAATCCGGCTGAGGAATGAGGACCTCGGCCTTCCTCCGCTCTTCCCGCCCCGGGAG
GCTTTCGCGGAGCAGTTTCTGCGTGGGAGTGATTACGCCATTCGCCTGGCGGCTCAGTCTACCTTAAGCT
TCTATCAGAGACGCCGCTTTTCCCCGGACGACTCGGCTGGAGCATCCGCCCTTCTGCGGTCGGGCCCCTA
CATGCCACAGTGTGATGCGTTTGGAAGTTGGGAGCCTGTGCAGTGCCACGCTGGGACTGGGCACTGCTGG
TGTGTAGATGAGAAAGGAGGGTTCATCCCTGGCTCACTGACTGCCCGCTCTCTGCAGATTCCACAGTGCC
CGACAACCTGCGAGAAATCTCGAACCAGTGGGCTGCTTTCCAGTTGGAAACAGGCTAGATCCCAAGAAAA
CCCATCTCCAAAAGACCTGTTCGTCCCAGCCTGCCTAGAAACAGGAGAGTATGCCAGGCTGCAGGCATCG
GGGGCTGGCACCTGGTGTGTGGACCCTGCATCAGGAGAAGAGTTGCGGCCTGGCTCGAGCAGCAGTGCCC
AGTGCCCAAGCCTCTGCAATGTGCTCAAGAGTGGAGTCCTCTCCAGGAGAGTCAGCCCAGGCTATGTCCC
AGCCTGCAGGGCAGAGGATGGGGGCTTTTCCCCAGTGCAATGTGACCAGGCCCAGGGCAGCTGCTGGTGT
GTCATGGACAGCGGAGAAGAGGTGCCTGGGACGCGCGTGACCGGGGGCCAGCCCGCCTGTGAGAGCCCGC
GGTGTCCGCTGCCATTCAACGCGTCGGAGGTGGTTGGTGGAACAATCCTGTGTGAGACAATCTCGGGCCC
CACAGGCTCTGCCATGCAGCAGTGCCAATTGCTGTGCCGCCAGGGCTCCTGGAGCGTGTTTCCACCAGGG
CCATTGATATGTAGCCTGGAGAGCGGACGCTGGGAGTCACAGCTGCCTCAGCCCCGGGCCTGCCAACGGC
CCCAGCTGTGGCAGACCATCCAGACCCAAGGGCACTTTCAGCTCCAGCTCCCGCCGGGCAAGATGTGCAG
TGCTGACTACGCGGATTTGCTGCAGACTTTCCAGGTTTTCATATTGGATGAGCTGACAGCCCGCGGCTTC
TGCCAGATCCAGGTGAAGACTTTTGGCACCCTGGTTTCCATTCCTGTCTGCAACAACTCCTCTGTGCAGG
TGGGTTGTCTGACCAGGGAGCGTTTAGGAGTGAATGTTACATGGAAATCACGGCTTGAGGACATCCCAGT
GGCTTCTCTTCCTGACTTACATGACATTGAGAGAGCCTTGGTGGGCAAGGATCTCCTTGGGCGCTTCACA
GATCTGATCCAGAGTGGCTCATTCCAGCTTCATCTGGACTCCAAGACGTTCCCAGCGGAAACCATCCGCT
TCCTCCAAGGGGACCACTTTGGCACCTCTCCCAGGACATGGTTTGGGTGCTCGGAAGGATTCTACCAAGT
CTTGACAAGTGAGGCCAGTCAGGACGGACTGGGATGCGTTAAGTGTCCTGAAGGAAGCTATTCCCAAGAT
GAGGAATGCATTCCTTGTCCTGTTGGATTCTACCAAGAACAGGCAGGGAGCTTGGCCTGTGTCCCATGTC
CTGTGGGCAGAACGACCATTTCTGCTGGAGCTTTCAGCCAGACTCACTGTGTCACTGACTGTCAGAGGAA
CGAAGCAGGCCTGCAATGTGACCAGAATGGCCAGTATCGAGCCAGCCAGAAGGACAGGGGCAGTGGGAAG
GCCTTCTGTGTGGACGGCGAGGGGCGGAGGCTGCCATGGTGGGAAACAGAGGCCCCTCTTGAGGACTCAC
AGTGTTTGATGATGCAGAAGTTTGAGAAGGTTCCAGAATCAAAGGTGATCTTCGACGCCAATGCTCCTGT
GGCTGTCAGATCCAAAGTTCCTGATTCTGAGTTCCCCGTGATGCAGTGCTTGACAGATTGCACAGAGGAC
GAGGCCTGCAGCTTCTTCACCGTGTCCACGACGGAGCCAGAGATTTCCTGTGATTTCTATGCTTGGACAA
GTGACAATGTTGCCTGCATGACTTCTGACCAGAAACGAGATGCACTGGGGAACTCAAAGGCCACCAGCTT
TGGAAGTCTTCGCTGCCAGGTGAAAGTGAGGAGCCATGGTCAAGATTCTCCAGCTGTGTATTTGAAAAAG
GGCCAAGGATCCACCACAACACTTCAGAAACGCTTTGAACCCACTGGTTTCCAAAACATGCTTTCTGGAT
TGTACAACCCCATTGTGTTCTCAGCCTCAGGAGCCAATCTAACCGATGCTCACCTCTTCTGTCTTCTTGC
ATGCGACCGTGATCTGTGTTGCGATGGCTTCGTCCTCACACAGGTTCAAGGAGGTGCCATCATCTGTGGG
TTGCTGAGCTCACCCAGTGTCCTGCTTTGTAATGTCAAAGACTGGATGGATCCCTCTGAAGCCTGGGCTA
ATGCTACATGTCCTGGTGTGACATATGACCAGGAGAGCCACCAGGTGATATTGCGTCTTGGAGACCAGGA
GTTCATCAAGAGTCTGACACCCTTAGAAGGAACTCAAGACACCTTTACCAATTTTCAGCAGGTTTATCTC
TGGAAAGATTCTGACATGGGGTCTCGGCCTGAGTCTATGGGATGTAGAAAAGACACAGTGCCAAGGCCAG
CATCTCCAACAGAAGCAGGTTTGACAACAGAACTTTTCTCCCCTGTGGACCTCAACCAGGTCATTGTCAA
TGGAAATCAATCACTATCCAGCCAGAAGCACTGGCTTTTCAAGCACCTGTTTTCAGCCCAGCAGGCAAAC
CTATGGTGCCTTTCTCGTTGTGTGCAGGAGCACTCTTTCTGTCAGCTCGCAGAGATAACAGAGAGTGCAT
CCTTGTACTTCACCTGCACCCTCTACCCAGAGGCACAGGTGTGTGATGACATCATGGAGTCCAATGCCCA
GGGCTGCAGACTGATCCTGCCTCAGATGCCAAAGGCCCTGTTCCGGAAGAAAGTTATACTGGAAGATAAA
GTGAAGAACTTTTACACTCGCCTGCCGTTCCAAAAACTGATGGGGATATCCATTAGAAATAAAGTGCCCA
TGTCTGAAAAATCTATTTCTAATGGGTTCTTTGAATGTGAACGACGGTGCGATGCGGACCCATGCTGCAC
TGGCTTTGGATTTCTAAATGTTTCCCAGTTAAAAGGAGGAGAGGTGACATGTCTCACTCTGAACAGCTTG
GGAATTCAGATGTGCAGTGAGGAGAATGGAGGAGCCTGGCGCATTTTGGACTGTGGCTCTCCTGACATTG
AAGTCCACACCTATCCCTTCGGATGGTACCAGAAGCCCATTGCTCAAAATAATGCTCCCAGTTTTTGCCC
TTTGGTTGTTCTGCCTTCCCTCACAGAGAAAGTGTCTCTGGACTCGTGGCAGTCCCTGGCCCTCTCTTCA
GTGGTTGTTGATCCATCCATTAGGCACTTTGATGTTGCCCATGTCAGCACTGCTGCCACCAGCAATTTCT
CTGCTGTCCGAGACCTCTGTTTGTCGGAATGTTCCCAACATGAGGCCTGTCTCATCACCACTCTGCAAAC
CCAACCTGGGGCTGTGAGATGTATGTTCTATGCTGATACTCAAAGCTGCACACATAGTCTGCAGGGTCAG
AACTGCCGACTTCTGCTTCGTGAAGAGGCCACCCACATCTACCGGAAGCCAGGAATCTCTCTGCTCAGCT
ATGAGGCATCTGTACCTTCTGTGCCCATTTCCACCCATGGCCGGCTGCTGGGCAGGTCCCAGGCCATCCA
GGTGGGTACCTCATGGAAGCAAGTGGACCAGTTCCTTGGAGTTCCATATGCTGCCCCGCCCCTGGCAGAG
AGGCGCTTCCAGGCACCAGAGCCCTTGAACTGGACAGGCTCCTGGGATGCCAGCAAGCCAAGGGCCAGCT
GCTGGCAGCCAGGCACCAGAACATCCACGTCTCCTGGAGTCAGTGAAGATTGTTTGTATCTCAATGTGTT
CATCCCTCAGAATGTGGCCCCTAACGCGTCTGTGCTGGTGTTCTTCCACAACACCATGGACAGGGAGGAG
AGTGAAGGATGGCCGGCTATCGACGGCTCCTTCTTGGCTGCTGTTGGCAACCTCATCGTGGTCACTGCCA
GCTACCGAGTGGGTGTCTTCGGCTTCCTGAGTTCTGGGTCCGGAGAGGTGAGTGGCAACTGGGGGCTGCT
GGACCAGGTGGCGGCTCTGACCTGGGTGCAGACCCACATCCGAGGATTTGGCGGGGACCCTCGGCGCGTG
TCCCTGGCAGCAGACCGTGGCGGGGCTGATGTGGCCAGCATCCACCTTCTCACGGCCAGGGCCACCAACT
CCCAACTTTTCCGGAGAGCTGTGCTGATGGGAGGCTCCGCACTCTCCCCGGCCGCCGTCATCAGCCATGA
GAGGGCTCAGCAGCAGGCAATTGCTTTGGCAAAGGAGGTCAGTTGCCCCATGTCATCCAGCCAAGAAGTG
GTGTCCTGCCTCCGCCAGAAGCCTGCCAATGTCCTCAATGATGCCCAGACCAAGCTCCTGGCCGTGAGTG
GCCCTTTCCACTACTGGGGTCCTGTGATCGATGGCCACTTCCTCCGTGAGCCTCCAGCCAGAGCACTGAA
GAGGTCTTTATGGGTAGAGGTCGATCTGCTCATTGGGAGTTCTCAGGACGACGGGCTCATCAACAGAGCA
AAGGCTGTGAAGCAATTTGAGGAAAGTCGAGGCCGGACCAGTAGCAAAACAGCCTTTTACCAGGCACTGC
AGAATTCTCTGGGTGGCGAGGACTCAGATGCCCGCGTCGAGGCTGCTGCTACATGGTATTACTCTCTGGA
GCACTCCACGGATGACTATGCCTCCTTCTCCCGGGCTCTGGAGAATGCCACCCGGGACTACTTTATCATC
TGCCCTATAATCGACATGGCCAGTGCCTGGGCAAAGAGGGCCCGAGGAAACGTCTTCATGTACCATGCTC
CTGAAAACTACGGCCATGGCAGCCTGGAGCTGCTGGCGGATGTTCAGTTTGCCTTGGGGCTTCCCTTCTA
CCCAGCCTACGAGGGGCAGTTTTCTCTGGAGGAGAAGAGCCTGTCGCTGAAAATCATGCAGTACTTTTCC
CACTTCATCAGATCAGGAAATCCCAACTACCCTTATGAGTTCTCACGGAAAGTACCCACATTTGCAACCC
CCTGGCCTGACTTTGTACCCCGTGCTGGTGGAGAGAACTACAAGGAGTTCAGTGAGCTGCTCCCCAATCG
ACAGGGCCTGAAGAAAGCCGACTGCTCCTTCTGGTCCAAGTACATCTCGTCTCTGAAGACATCTGCAGAT
GGAGCCAAGGGCGGGCAGTCAGCAGAGAGTGAAGAGGAGGAGTTGACGGCTGGATCTGGGCTAAGAGAAG
ATCTCCTAAGCCTCCAGGAACCAGGCTCTAAGACCTACAGCAAGTGA翻译后氨基酸参数序列: 点击查看序列ATGGCCCTGGTCCTGGAGATCTTCACCCTGCTGGCCTCCATCTGCTGGGTGTCGGCCAATATCTTCGAGT
ACCAGGTGGATGCCCAGCCCCTTCGTCCCTGTGAGCTGCAGAGGGAAACGGCCTTTCTGAAGCAAGCAGA
CTACGTGCCCCAGTGTGCAGAGGATGGCAGCTTCCAGACTGTCCAGTGCCAGAACGACGGCCGCTCCTGC
TGGTGTGTGGGTGCCAACGGCAGTGAAGTGCTGGGCAGCAGGCAGCCAGGACGGCCTGTGGCTTGTCTGT
CATTTTGTCAGCTACAGAAACAGCAGATCTTACTGAGTGGCTACATTAACAGCACAGACACCTCCTACCT
CCCTCAGTGTCAGGATTCAGGGGACTACGCGCCTGTTCAGTGTGATGTGCAGCAGGTCCAGTGCTGGTGT
GTGGACGCAGAGGGGATGGAGGTGTATGGGACCCGCCAGCTGGGGAGGCCAAAGCGATGTCCAAGGAGCT
GTGAAATAAGAAATCGTCGTCTTCTCCACGGGGTGGGAGATAAGTCACCACCCCAGTGTTCTGCGGAGGG
AGAGTTTATGCCTGTCCAGTGCAAATTTGTCAACACCACAGACATGATGATTTTTGATCTGGTCCACAGC
TACAACAGGTTTCCAGATGCATTTGTGACCTTCAGTTCCTTCCAGAGGAGGTTCCCTGAGGTATCTGGGT
ATTGCCACTGTGCTGACAGCCAAGGGCGGGAACTGGCTGAGACAGGTTTGGAGTTGTTACTGGATGAAAT
TTATGACACCATTTTTGCTGGCCTGGACCTTCCTTCCACCTTCACTGAAACCACCCTGTACCGGATACTG
CAGAGACGGTTCCTCGCAGTTCAATCAGTCATCTCTGGCAGATTCCGATGCCCCACAAAATGTGAAGTGG
AGCGGTTTACAGCAACCAGCTTTGGTCACCCCTATGTTCCAAGCTGCCGCCGAAATGGCGACTATCAGGC
GGTGCAGTGCCAGACGGAAGGGCCCTGCTGGTGTGTGGACGCCCAGGGGAAGGAAATGCATGGAACCCGG
CAGCAAGGGGAGCCGCCATCTTGTGCTGAAGGCCAATCTTGTGCCTCCGAAAGGCAGCAGGCCTTGTCCA
GACTCTACTTTGGGACCTCAGGCTACTTCAGCCAGCACGACCTGTTCTCTTCCCCAGAGAAAAGATGGGC
CTCTCCAAGAGTAGCCAGATTTGCCACATCCTGCCCACCCACGATCAAGGAGCTCTTTGTGGACTCTGGG
CTTCTCCGCCCAATGGTGGAGGGACAGAGCCAACAGTTTTCTGTCTCAGAAAATCTTCTCAAAGAAGCCA
TCCGAGCAATTTTTCCCTCCCGAGGGCTGGCTCGTCTTGCCCTTCAGTTTACCACCAACCCAAAGAGACT
CCAGCAAAACCTTTTTGGAGGGAAATTTTTGGTGAATGTTGGCCAGTTTAACTTGTCTGGAGCCCTTGGC
ACAAGAGGCACATTTAACTTCAGTCAATTTTTCCAGCAACTTGGTCTTGCAAGCTTCTTGAATGGAGGGA
GACAAGAAGATTTGGCCAAGCCACTCTCTGTGGGATTAGATTCAAATTCTTCCACAGGAACCCCTGAAGC
TGCTAAGAAGGATGGTACTATGAATAAGCCAACTGTGGGCAGCTTTGGCTTTGAAATTAACCTACAAGAG
AACCAAAATGCCCTCAAATTCCTTGCTTCTCTCCTGGAGCTTCCAGAATTCCTTCTCTTCTTGCAACATG
CTATCTCTGTGCCAGAAGATGTGGCAAGAGATTTAGGTGATGTGATGGAAACGGTACTCAGCTCCCAGAC
CTGTGAGCAGACACCTGAAAGGCTATTTGTCCCATCATGCACGACAGAAGGAAGCTATGAGGATGTCCAA
TGCTTTTCCGGAGAGTGCTGGTGTGTGAATTCCTGGGGCAAAGAGCTTCCAGGCTCAAGAGTCAGAGGTG
GACAGCCAAGGTGCCCCACAGACTGTGAAAAGCAAAGGGCTCGCATGCAAAGCCTCATGGGCAGCCAGCC
TGCTGGCTCCACCTTGTTTGTCCCTGCTTGTACTAGTGAGGGACATTTCCTGCCTGTCCAGTGCTTCAAC
TCAGAGTGCTACTGTGTTGATGCTGAGGGTCAGGCCATTCCTGGAACTCGAAGTGCAATAGGGAAGCCCA
AGAAATGCCCCACGCCCTGTCAATTACAGTCTGAGCAAGCTTTCCTCAGGACGGTGCAGGCCCTGCTCTC
TAACTCCAGCATGCTACCCACCCTTTCCGACACCTACATCCCACAGTGCAGCACCGATGGGCAGTGGAGA
CAAGTGCAATGCAATGGGCCTCCTGAGCAGGTCTTCGAGTTGTACCAACGATGGGAGGCTCAGAACAAGG
GCCAGGATCTGACGCCTGCCAAGCTGCTAGTGAAGATCATGAGCTACAGAGAAGCAGCTTCCGGAAACTT
CAGTCTCTTTATTCAAAGTCTGTATGAGGCTGGCCAGCAAGATGTCTTCCCGGTGCTGTCACAATACCCT
TCTCTGCAAGATGTCCCACTAGCAGCACTGGAAGGGAAACGGCCCCAGCCCAGGGAGAATATCCTCCTGG
AGCCCTACCTCTTCTGGCAGATCTTAAATGGCCAACTCAGCCAATACCCGGGGTCCTACTCAGACTTCAG
CACTCCTTTGGCACATTTTGATCTTCGGAACTGCTGGTGTGTGGATGAGGCTGGCCAAGAACTGGAAGGA
ATGCGGTCTGAGCCAAGCAAGCTCCCAACATGTCCTGGCTCCTGTGAGGAAGCAAAGCTCCGTGTACTGC
AGTTCATTAGGGAAACGGAAGAGATTGTTTCAGCTTCCAACAGTTCTCGGTTCCCTCTGGGGGAGAGTTT
CCTGGTGGCCAAGGGAATCCGGCTGAGGAATGAGGACCTCGGCCTTCCTCCGCTCTTCCCGCCCCGGGAG
GCTTTCGCGGAGCAGTTTCTGCGTGGGAGTGATTACGCCATTCGCCTGGCGGCTCAGTCTACCTTAAGCT
TCTATCAGAGACGCCGCTTTTCCCCGGACGACTCGGCTGGAGCATCCGCCCTTCTGCGGTCGGGCCCCTA
CATGCCACAGTGTGATGCGTTTGGAAGTTGGGAGCCTGTGCAGTGCCACGCTGGGACTGGGCACTGCTGG
TGTGTAGATGAGAAAGGAGGGTTCATCCCTGGCTCACTGACTGCCCGCTCTCTGCAGATTCCACAGTGCC
CGACAACCTGCGAGAAATCTCGAACCAGTGGGCTGCTTTCCAGTTGGAAACAGGCTAGATCCCAAGAAAA
CCCATCTCCAAAAGACCTGTTCGTCCCAGCCTGCCTAGAAACAGGAGAGTATGCCAGGCTGCAGGCATCG
GGGGCTGGCACCTGGTGTGTGGACCCTGCATCAGGAGAAGAGTTGCGGCCTGGCTCGAGCAGCAGTGCCC
AGTGCCCAAGCCTCTGCAATGTGCTCAAGAGTGGAGTCCTCTCCAGGAGAGTCAGCCCAGGCTATGTCCC
AGCCTGCAGGGCAGAGGATGGGGGCTTTTCCCCAGTGCAATGTGACCAGGCCCAGGGCAGCTGCTGGTGT
GTCATGGACAGCGGAGAAGAGGTGCCTGGGACGCGCGTGACCGGGGGCCAGCCCGCCTGTGAGAGCCCGC
GGTGTCCGCTGCCATTCAACGCGTCGGAGGTGGTTGGTGGAACAATCCTGTGTGAGACAATCTCGGGCCC
CACAGGCTCTGCCATGCAGCAGTGCCAATTGCTGTGCCGCCAGGGCTCCTGGAGCGTGTTTCCACCAGGG
CCATTGATATGTAGCCTGGAGAGCGGACGCTGGGAGTCACAGCTGCCTCAGCCCCGGGCCTGCCAACGGC
CCCAGCTGTGGCAGACCATCCAGACCCAAGGGCACTTTCAGCTCCAGCTCCCGCCGGGCAAGATGTGCAG
TGCTGACTACGCGGATTTGCTGCAGACTTTCCAGGTTTTCATATTGGATGAGCTGACAGCCCGCGGCTTC
TGCCAGATCCAGGTGAAGACTTTTGGCACCCTGGTTTCCATTCCTGTCTGCAACAACTCCTCTGTGCAGG
TGGGTTGTCTGACCAGGGAGCGTTTAGGAGTGAATGTTACATGGAAATCACGGCTTGAGGACATCCCAGT
GGCTTCTCTTCCTGACTTACATGACATTGAGAGAGCCTTGGTGGGCAAGGATCTCCTTGGGCGCTTCACA
GATCTGATCCAGAGTGGCTCATTCCAGCTTCATCTGGACTCCAAGACGTTCCCAGCGGAAACCATCCGCT
TCCTCCAAGGGGACCACTTTGGCACCTCTCCCAGGACATGGTTTGGGTGCTCGGAAGGATTCTACCAAGT
CTTGACAAGTGAGGCCAGTCAGGACGGACTGGGATGCGTTAAGTGTCCTGAAGGAAGCTATTCCCAAGAT
GAGGAATGCATTCCTTGTCCTGTTGGATTCTACCAAGAACAGGCAGGGAGCTTGGCCTGTGTCCCATGTC
CTGTGGGCAGAACGACCATTTCTGCTGGAGCTTTCAGCCAGACTCACTGTGTCACTGACTGTCAGAGGAA
CGAAGCAGGCCTGCAATGTGACCAGAATGGCCAGTATCGAGCCAGCCAGAAGGACAGGGGCAGTGGGAAG
GCCTTCTGTGTGGACGGCGAGGGGCGGAGGCTGCCATGGTGGGAAACAGAGGCCCCTCTTGAGGACTCAC
AGTGTTTGATGATGCAGAAGTTTGAGAAGGTTCCAGAATCAAAGGTGATCTTCGACGCCAATGCTCCTGT
GGCTGTCAGATCCAAAGTTCCTGATTCTGAGTTCCCCGTGATGCAGTGCTTGACAGATTGCACAGAGGAC
GAGGCCTGCAGCTTCTTCACCGTGTCCACGACGGAGCCAGAGATTTCCTGTGATTTCTATGCTTGGACAA
GTGACAATGTTGCCTGCATGACTTCTGACCAGAAACGAGATGCACTGGGGAACTCAAAGGCCACCAGCTT
TGGAAGTCTTCGCTGCCAGGTGAAAGTGAGGAGCCATGGTCAAGATTCTCCAGCTGTGTATTTGAAAAAG
GGCCAAGGATCCACCACAACACTTCAGAAACGCTTTGAACCCACTGGTTTCCAAAACATGCTTTCTGGAT
TGTACAACCCCATTGTGTTCTCAGCCTCAGGAGCCAATCTAACCGATGCTCACCTCTTCTGTCTTCTTGC
ATGCGACCGTGATCTGTGTTGCGATGGCTTCGTCCTCACACAGGTTCAAGGAGGTGCCATCATCTGTGGG
TTGCTGAGCTCACCCAGTGTCCTGCTTTGTAATGTCAAAGACTGGATGGATCCCTCTGAAGCCTGGGCTA
ATGCTACATGTCCTGGTGTGACATATGACCAGGAGAGCCACCAGGTGATATTGCGTCTTGGAGACCAGGA
GTTCATCAAGAGTCTGACACCCTTAGAAGGAACTCAAGACACCTTTACCAATTTTCAGCAGGTTTATCTC
TGGAAAGATTCTGACATGGGGTCTCGGCCTGAGTCTATGGGATGTAGAAAAGACACAGTGCCAAGGCCAG
CATCTCCAACAGAAGCAGGTTTGACAACAGAACTTTTCTCCCCTGTGGACCTCAACCAGGTCATTGTCAA
TGGAAATCAATCACTATCCAGCCAGAAGCACTGGCTTTTCAAGCACCTGTTTTCAGCCCAGCAGGCAAAC
CTATGGTGCCTTTCTCGTTGTGTGCAGGAGCACTCTTTCTGTCAGCTCGCAGAGATAACAGAGAGTGCAT
CCTTGTACTTCACCTGCACCCTCTACCCAGAGGCACAGGTGTGTGATGACATCATGGAGTCCAATGCCCA
GGGCTGCAGACTGATCCTGCCTCAGATGCCAAAGGCCCTGTTCCGGAAGAAAGTTATACTGGAAGATAAA
GTGAAGAACTTTTACACTCGCCTGCCGTTCCAAAAACTGATGGGGATATCCATTAGAAATAAAGTGCCCA
TGTCTGAAAAATCTATTTCTAATGGGTTCTTTGAATGTGAACGACGGTGCGATGCGGACCCATGCTGCAC
TGGCTTTGGATTTCTAAATGTTTCCCAGTTAAAAGGAGGAGAGGTGACATGTCTCACTCTGAACAGCTTG
GGAATTCAGATGTGCAGTGAGGAGAATGGAGGAGCCTGGCGCATTTTGGACTGTGGCTCTCCTGACATTG
AAGTCCACACCTATCCCTTCGGATGGTACCAGAAGCCCATTGCTCAAAATAATGCTCCCAGTTTTTGCCC
TTTGGTTGTTCTGCCTTCCCTCACAGAGAAAGTGTCTCTGGACTCGTGGCAGTCCCTGGCCCTCTCTTCA
GTGGTTGTTGATCCATCCATTAGGCACTTTGATGTTGCCCATGTCAGCACTGCTGCCACCAGCAATTTCT
CTGCTGTCCGAGACCTCTGTTTGTCGGAATGTTCCCAACATGAGGCCTGTCTCATCACCACTCTGCAAAC
CCAACCTGGGGCTGTGAGATGTATGTTCTATGCTGATACTCAAAGCTGCACACATAGTCTGCAGGGTCAG
AACTGCCGACTTCTGCTTCGTGAAGAGGCCACCCACATCTACCGGAAGCCAGGAATCTCTCTGCTCAGCT
ATGAGGCATCTGTACCTTCTGTGCCCATTTCCACCCATGGCCGGCTGCTGGGCAGGTCCCAGGCCATCCA
GGTGGGTACCTCATGGAAGCAAGTGGACCAGTTCCTTGGAGTTCCATATGCTGCCCCGCCCCTGGCAGAG
AGGCGCTTCCAGGCACCAGAGCCCTTGAACTGGACAGGCTCCTGGGATGCCAGCAAGCCAAGGGCCAGCT
GCTGGCAGCCAGGCACCAGAACATCCACGTCTCCTGGAGTCAGTGAAGATTGTTTGTATCTCAATGTGTT
CATCCCTCAGAATGTGGCCCCTAACGCGTCTGTGCTGGTGTTCTTCCACAACACCATGGACAGGGAGGAG
AGTGAAGGATGGCCGGCTATCGACGGCTCCTTCTTGGCTGCTGTTGGCAACCTCATCGTGGTCACTGCCA
GCTACCGAGTGGGTGTCTTCGGCTTCCTGAGTTCTGGGTCCGGAGAGGTGAGTGGCAACTGGGGGCTGCT
GGACCAGGTGGCGGCTCTGACCTGGGTGCAGACCCACATCCGAGGATTTGGCGGGGACCCTCGGCGCGTG
TCCCTGGCAGCAGACCGTGGCGGGGCTGATGTGGCCAGCATCCACCTTCTCACGGCCAGGGCCACCAACT
CCCAACTTTTCCGGAGAGCTGTGCTGATGGGAGGCTCCGCACTCTCCCCGGCCGCCGTCATCAGCCATGA
GAGGGCTCAGCAGCAGGCAATTGCTTTGGCAAAGGAGGTCAGTTGCCCCATGTCATCCAGCCAAGAAGTG
GTGTCCTGCCTCCGCCAGAAGCCTGCCAATGTCCTCAATGATGCCCAGACCAAGCTCCTGGCCGTGAGTG
GCCCTTTCCACTACTGGGGTCCTGTGATCGATGGCCACTTCCTCCGTGAGCCTCCAGCCAGAGCACTGAA
GAGGTCTTTATGGGTAGAGGTCGATCTGCTCATTGGGAGTTCTCAGGACGACGGGCTCATCAACAGAGCA
AAGGCTGTGAAGCAATTTGAGGAAAGTCGAGGCCGGACCAGTAGCAAAACAGCCTTTTACCAGGCACTGC
AGAATTCTCTGGGTGGCGAGGACTCAGATGCCCGCGTCGAGGCTGCTGCTACATGGTATTACTCTCTGGA
GCACTCCACGGATGACTATGCCTCCTTCTCCCGGGCTCTGGAGAATGCCACCCGGGACTACTTTATCATC
TGCCCTATAATCGACATGGCCAGTGCCTGGGCAAAGAGGGCCCGAGGAAACGTCTTCATGTACCATGCTC
CTGAAAACTACGGCCATGGCAGCCTGGAGCTGCTGGCGGATGTTCAGTTTGCCTTGGGGCTTCCCTTCTA
CCCAGCCTACGAGGGGCAGTTTTCTCTGGAGGAGAAGAGCCTGTCGCTGAAAATCATGCAGTACTTTTCC
CACTTCATCAGATCAGGAAATCCCAACTACCCTTATGAGTTCTCACGGAAAGTACCCACATTTGCAACCC
CCTGGCCTGACTTTGTACCCCGTGCTGGTGGAGAGAACTACAAGGAGTTCAGTGAGCTGCTCCCCAATCG
ACAGGGCCTGAAGAAAGCCGACTGCTCCTTCTGGTCCAAGTACATCTCGTCTCTGAAGACATCTGCAGAT
GGAGCCAAGGGCGGGCAGTCAGCAGAGAGTGAAGAGGAGGAGTTGACGGCTGGATCTGGGCTAAGAGAAG
ATCTCCTAAGCCTCCAGGAACCAGGCTCTAAGACCTACAGCAAGTGA