• 商品货号：G163537

• accession：NM_007124
• 基因别名：DRP; DMDL; DRP1
• 基因描述：Homo sapiens utrophin (UTRN), mRNA.
• 载体：现货载体
• CDS区长度：10302
• 翻译后氨基酸长度：3433
• 基因简介：This gene shares both structural and functional similarities with the dystrophin gene. It contains an actin-binding N-terminus, a triple coiled-coil repeat central region, and a C-terminus that consists of protein-protein interaction motifs which interact with dystroglycan protein components. The protein encoded by this gene is located at the neuromuscular synapse and myotendinous junctions, where it participates in post-synaptic membrane maintenance and acetylcholine receptor clustering. Mouse studies suggest that this gene may serve as a functional substitute for the dystrophin gene and therefore, may serve as a potential therapeutic alternative to muscular dystrophy which is caused by mutations in the dystrophin gene. Alternative splicing of the utrophin gene has been described; however, the full-length nature of these variants has not yet been determined. [provided by RefSeq, Jul 2008]
• 规格：10ul 质粒

CDS区参考序列： 点击查看序列

ATGGCCAAGTATGGAGAACATGAAGCCAGTCCTGACAATGGGCAGAACGAATTCAGTGATATCATTAAGT
CCAGATCTGATGAACACAATGACGTACAGAAGAAAACCTTTACCAAATGGATAAATGCTCGATTTTCAAA
GAGTGGGAAACCACCCATCAATGATATGTTCACAGACCTCAAAGATGGAAGGAAGCTATTGGATCTTCTA
GAAGGCCTCACAGGAACATCACTGCCAAAGGAACGTGGTTCCACAAGGGTACATGCCTTAAATAACGTCA
ACAGAGTGCTGCAGGTTTTACATCAGAACAATGTGGAATTAGTGAATATAGGGGGAACTGACATTGTGGA
TGGAAATCACAAACTGACTTTGGGGTTACTTTGGAGCATCATTTTGCACTGGCAGGTGAAAGATGTCATG
AAGGATGTCATGTCGGACCTGCAGCAGACGAACAGTGAGAAGATCCTGCTCAGCTGGGTGCGTCAGACCA
CCAGGCCCTACAGCCAAGTCAACGTCCTCAACTTCACCACCAGCTGGACAGATGGACTCGCCTTTAATGC
TGTCCTCCACCGACATAAACCTGATCTCTTCAGCTGGGATAAAGTTGTCAAAATGTCACCAATTGAGAGA
CTTGAACATGCCTTCAGCAAGGCTCAAACTTATTTGGGAATTGAAAAGCTGTTAGATCCTGAAGATGTTG
CCGTTCAGCTTCCTGACAAGAAATCCATAATTATGTATTTAACATCTTTGTTTGAGGTGCTACCTCAGCA
AGTCACCATAGACGCCATCCGTGAGGTAGAGACACTCCCAAGGAAATATAAAAAAGAATGTGAAGAAGAG
GCAATTAATATACAGAGTACAGCGCCTGAGGAGGAGCATGAGAGTCCCCGAGCTGAAACTCCCAGCACTG
TCACTGAGGTTGACATGGATCTGGACAGCTATCAGATTGCGTTGGAGGAAGTGCTGACCTGGTTGCTTTC
TGCTGAGGACACTTTCCAGGAGCAGGATGATATTTCTGATGATGTTGAAGAAGTCAAAGACCAGTTTGCA
ACCCATGAAGCTTTTATGATGGAACTGACTGCACACCAGAGCAGTGTGGGCAGCGTCCTGCAGGCAGGCA
ACCAACTGATAACACAAGGAACTCTGTCAGACGAAGAAGAATTTGAGATTCAGGAACAGATGACCCTGCT
GAATGCTAGATGGGAGGCTCTTAGGGTGGAGAGTATGGACAGACAGTCCCGGCTGCACGATGTGCTGATG
GAACTGCAGAAGAAGCAACTGCAGCAGCTCTCCGCCTGGTTAACACTCACAGAGGAGCGCATTCAGAAGA
TGGAAACTTGCCCCCTGGATGATGATGTAAAATCTCTACAAAAGCTGCTAGAAGAACATAAAAGTTTGCA
AAGTGATCTTGAGGCTGAACAGGTGAAAGTAAATTCACTAACTCACATGGTGGTCATTGTTGATGAAAAC
AGTGGTGAGAGTGCTACAGCTATCCTAGAAGACCAGTTACAGAAACTTGGTGAGCGCTGGACAGCAGTAT
GCCGTTGGACTGAAGAACGCTGGAATAGGTTACAAGAAATCAATATATTGTGGCAGGAATTATTGGAAGA
ACAGTGCTTGTTGAAAGCTTGGTTAACCGAAAAAGAAGAGGCTTTAAATAAAGTCCAGACAAGCAACTTC
AAAGACCAAAAGGAACTAAGTGTCAGTGTTCGACGTCTGGCTATTTTGAAGGAAGACATGGAAATGAAGC
GTCAAACATTGGATCAGCTGAGTGAGATTGGCCAGGATGTGGGACAATTACTTGATAATTCCAAGGCATC
TAAGAAGATCAACAGTGACTCAGAGGAACTGACTCAAAGATGGGATTCTTTGGTTCAGAGACTAGAAGAT
TCCTCCAACCAGGTGACTCAGGCTGTAGCAAAGCTGGGGATGTCTCAGATTCCTCAGAAGGACCTTTTGG
AGACTGTTCGTGTAAGAGAACAAGCAATTACAAAAAAATCTAAGCAGGAACTGCCTCCTCCTCCTCCCCC
AAAGAAGAGACAGATCCATGTGGATATTGAAGCTAAGAAAAAGTTTGATGCTATAAGTGCAGAGCTGTTG
AACTGGATTTTGAAATGGAAAACTGCCATTCAGACCACAGAGATAAAAGAGTATATGAAGATGCAAGACA
CTTCCGAAATGAAAAAGAAGTTGAAGGCATTAGAAAAAGAACAGAGAGAAAGAATCCCCAGAGCAGATGA
ATTAAACCAAACTGGACAAATCCTTGTGGAGCAAATGGGAAAAGAAGGCCTTCCTACTGAAGAAATAAAA
AATGTTCTGGAGAAGGTTTCATCAGAATGGAAGAATGTATCTCAACATTTGGAAGATCTAGAAAGAAAGA
TTCAGCTACAGGAAGATATAAATGCTTATTTCAAGCAGCTTGATGAGCTTGAAAAGGTCATCAAGACAAA
GGAGGAGTGGGTAAAACACACTTCCATTTCTGAATCTTCCCGGCAGTCCTTGCCAAGCTTGAAGGATTCC
TGTCAGCGGGAATTGACAAATCTTCTTGGCCTTCACCCCAAAATTGAAATGGCTCGTGCAAGCTGCTCGG
CCCTGATGTCTCAGCCTTCTGCCCCAGATTTTGTCCAGCGGGGCTTCGATAGCTTTCTGGGCCGCTACCA
AGCTGTACAAGAGGCTGTAGAGGATCGTCAACAACATCTAGAGAATGAACTGAAGGGCCAACCTGGACAT
GCATATCTGGAAACATTGAAAACACTGAAAGATGTGCTAAATGATTCAGAAAATAAGGCCCAGGTGTCTC
TGAATGTCCTTAATGATCTTGCCAAGGTGGAGAAGGCCCTGCAAGAAAAAAAGACCCTTGATGAAATCCT
TGAGAATCAGAAACCTGCATTACATAAACTTGCAGAAGAAACAAAGGCTCTGGAGAAAAATGTTCATCCT
GATGTAGAAAAATTATATAAGCAAGAATTTGATGATGTGCAAGGAAAGTGGAACAAGCTAAAGGTCTTGG
TTTCCAAAGATCTACATTTGCTTGAGGAAATTGCTCTCACACTCAGAGCTTTTGAGGCCGATTCAACAGT
CATTGAGAAGTGGATGGATGGCGTGAAAGACTTCTTAATGAAACAGCAGGCTGCCCAAGGAGACGACGCA
GGTCTACAGAGGCAGTTAGACCAGTGCTCTGCATTTGTTAATGAAATAGAAACAATTGAATCATCTCTGA
AAAACATGAAGGAAATAGAGACTAATCTTCGAAGTGGTCCAGTTGCTGGAATAAAAACTTGGGTGCAGAC
AAGACTAGGTGACTACCAAACTCAACTGGAGAAACTTAGCAAGGAGATCGCTACTCAAAAAAGTAGGTTG
TCTGAAAGTCAAGAAAAAGCTGCGAACCTGAAGAAAGACTTGGCAGAGATGCAGGAATGGATGACCCAGG
CCGAGGAAGAATATTTGGAGCGGGATTTTGAGTACAAGTCACCAGAAGAGCTTGAGAGTGCTGTGGAAGA
GATGAAGAGGGCAAAAGAGGATGTGTTGCAGAAGGAGGTGAGAGTGAAGATTCTCAAGGACAACATCAAG
TTATTAGCTGCCAAGGTGCCCTCTGGTGGCCAGGAGTTGACGTCTGAGCTGAATGTTGTGCTGGAGAATT
ACCAACTTCTTTGTAATAGAATTCGAGGAAAGTGCCACACGCTAGAGGAGGTCTGGTCTTGTTGGATTGA
ACTGCTTCACTATTTGGATCTTGAAACTACCTGGTTAAACACTTTGGAAGAGCGGATGAAGAGCACAGAG
GTCCTGCCTGAGAAGACGGATGCTGTCAACGAAGCCCTGGAGTCTCTGGAATCTGTTCTGCGCCACCCGG
CAGATAATCGCACCCAGATTCGAGAGCTTGGCCAGACTCTGATTGATGGGGGGATCCTGGATGATATAAT
CAGTGAGAAACTGGAGGCTTTCAACAGCCGATATGAAGATCTAAGTCACCTGGCAGAGAGCAAGCAGATT
TCTTTGGAAAAGCAACTCCAGGTGCTGCGGGAAACTGACCAGATGCTTCAAGTCTTGCAAGAGAGCTTGG
GGGAGCTGGACAAACAGCTCACCACATACCTGACTGACAGGATAGATGCTTTCCAAGTTCCACAGGAAGC
TCAGAAAATCCAAGCAGAGATCTCAGCCCATGAGCTAACCCTAGAGGAGTTGAGAAGAAATATGCGTTCT
CAGCCCCTGACCTCCCCAGAGAGTAGGACTGCCAGAGGAGGAAGTCAGATGGATGTGCTACAGAGGAAAC
TCCGAGAGGTGTCCACAAAGTTCCAGCTTTTCCAGAAGCCAGCTAACTTCGAGCAGCGCATGCTGGACTG
CAAGCGTGTGCTGGATGGCGTGAAAGCAGAACTTCACGTTCTGGATGTGAAGGACGTAGACCCTGACGTC
ATACAGACGCACCTGGACAAGTGTATGAAACTGTATAAAACTTTGAGTGAAGTCAAACTTGAAGTGGAAA
CTGTGATTAAAACAGGAAGACATATTGTCCAGAAACAGCAAACGGACAACCCAAAAGGGATGGATGAGCA
GCTGACTTCCCTGAAGGTTCTTTACAATGACCTGGGCGCACAGGTGACAGAAGGAAAACAGGATCTGGAA
AGAGCATCACAGTTGGCCCGGAAAATGAAGAAAGAGGCTGCTTCTCTCTCTGAATGGCTTTCTGCTACTG
AAACTGAATTGGTACAGAAGTCCACTTCAGAAGGTCTGCTTGGTGACTTGGATACAGAAATTTCCTGGGC
TAAAAATGTTCTGAAGGATCTGGAAAAGAGAAAAGCTGATTTAAATACCATCACAGAGAGTAGTGCTGCC
CTGCAAAACTTGATTGAGGGCAGTGAGCCTATTTTAGAAGAGAGGCTCTGCGTCCTTAACGCTGGGTGGA
GCCGAGTTCGTACCTGGACTGAAGATTGGTGCAATACCTTGATGAACCATCAGAACCAGCTAGAAATATT
TGATGGGAACGTGGCTCACATAAGTACCTGGCTTTATCAAGCTGAAGCTCTATTGGATGAAATTGAAAAG
AAACCAACAAGTAAACAGGAAGAAATTGTGAAGCGTTTAGTATCTGAGCTGGATGATGCCAACCTCCAGG
TTGAAAATGTCCGCGATCAAGCCCTTATTTTGATGAATGCCCGTGGAAGCTCAAGCAGGGAGCTTGTAGA
ACCAAAGTTAGCTGAGCTGAATAGGAACTTTGAAAAGGTGTCTCAACATATCAAAAGTGCCAAATTGCTA
ATTGCTCAGGAACCATTATACCAATGTTTGGTCACCACTGAAACATTTGAAACTGGTGTGCCTTTCTCTG
ACTTGGAAAAATTAGAAAATGACATAGAAAATATGTTAAAATTTGTGGAAAAACACTTGGAATCCAGTGA
TGAAGATGAAAAGATGGATGAGGAGAGTGCCCAGATTGAGGAAGTTCTACAAAGAGGAGAAGAAATGTTA
CATCAACCTATGGAAGATAATAAAAAAGAAAAGATCCGTTTGCAATTATTACTTTTGCATACTAGATACA
ACAAAATTAAGGCAATCCCTATTCAACAGAGGAAAATGGGTCAACTTGCTTCTGGAATTAGATCATCACT
TCTTCCTACAGATTATCTGGTTGAAATTAACAAAATTTTACTTTGCATGGATGATGTTGAATTATCGCTT
AATGTTCCAGAGCTCAACACTGCTATTTACGAAGACTTCTCTTTTCAGGAAGACTCTCTGAAGAATATCA
AAGACCAACTGGACAAACTTGGAGAGCAGATTGCAGTCATTCATGAAAAACAGCCAGATGTCATCCTTGA
AGCCTCTGGACCTGAAGCCATTCAGATCAGAGATACACTTACTCAGCTGAATGCAAAATGGGACAGAATT
AATAGAATGTACAGTGATCGGAAAGGTTGTTTTGACAGGGCAATGGAAGAATGGAGACAGTTCCATTGTG
ACCTTAATGACCTCACACAGTGGATAACAGAGGCTGAAGAATTACTGGTTGATACCTGTGCTCCAGGTGG
CAGCCTGGACTTAGAGAAAGCCAGGATACATCAGCAGGAACTTGAGGTGGGCATCAGCAGCCACCAGCCC
AGTTTTGCAGCACTAAACCGAACTGGGGATGGGATTGTGCAGAAACTCTCCCAGGCAGATGGAAGCTTCT
TGAAAGAAAAACTGGCAGGTTTAAACCAACGCTGGGATGCAATTGTTGCAGAAGTGAAGGATAGGCAGCC
AAGGCTAAAAGGAGAAAGTAAGCAGGTGATGAAGTACAGGCATCAGCTAGATGAGATTATCTGTTGGTTA
ACAAAGGCTGAGCATGCTATGCAAAAGAGATCAACCACCGAATTGGGAGAAAACCTGCAAGAATTAAGAG
ACTTAACTCAAGAAATGGAAGTACATGCTGAAAAACTCAAATGGCTGAATAGAACTGAATTGGAGATGCT
TTCAGATAAAAGTCTGAGTTTACCTGAAAGGGATAAAATTTCAGAAAGCTTAAGGACTGTAAATATGACA
TGGAATAAGATTTGCAGAGAGGTGCCTACCACCCTGAAGGAATGCATCCAGGAGCCCAGTTCTGTTTCAC
AGACAAGGATTGCTGCTCATCCTAATGTCCAAAAGGTGGTGCTAGTATCATCTGCGTCAGATATTCCTGT
TCAGTCTCATCGTACTTCGGAAATTTCAATTCCTGCTGATCTTGATAAAACTATAACAGAACTAGCCGAC
TGGCTGGTATTAATCGACCAGATGCTGAAGTCCAACATTGTCACTGTTGGGGATGTAGAAGAGATCAATA
AGACCGTTTCCCGAATGAAAATTACAAAGGCTGACTTAGAACAGCGCCATCCTCAGCTGGATTATGTTTT
TACATTGGCACAGAATTTGAAAAATAAAGCTTCCAGTTCAGATATGAGAACAGCAATTACAGAAAAATTG
GAAAGGGTCAAGAACCAGTGGGATGGCACCCAGCATGGCGTTGAGCTAAGACAGCAGCAGCTTGAGGACA
TGATTATTGACAGTCTTCAGTGGGATGACCATAGGGAGGAGACTGAAGAACTGATGAGAAAATATGAGGC
TCGACTCTATATTCTTCAGCAAGCCCGACGGGATCCACTCACCAAACAAATTTCTGATAACCAAATACTG
CTTCAAGAACTGGGTCCTGGAGATGGTATCGTCATGGCGTTCGATAACGTCCTGCAGAAACTCCTGGAGG
AATATGGGAGTGATGACACAAGGAATGTGAAAGAAACCACAGAGTACTTAAAAACATCATGGATCAATCT
CAAACAAAGTATTGCTGACAGACAGAACGCCTTGGAGGCTGAGTGGAGGACGGTGCAGGCCTCTCGCAGA
GATCTGGAAAACTTCCTGAAGTGGATCCAAGAAGCAGAGACCACAGTGAATGTGCTTGTGGATGCCTCTC
ATCGGGAGAATGCTCTTCAGGATAGTATCTTGGCCAGGGAACTCAAACAGCAGATGCAGGACATCCAGGC
AGAAATTGATGCCCACAATGACATATTTAAAAGCATTGACGGAAACAGGCAGAAGATGGTAAAAGCTTTG
GGAAATTCTGAAGAGGCTACTATGCTTCAACATCGACTGGATGATATGAACCAAAGATGGAATGACTTAA
AAGCAAAATCTGCTAGCATCAGGGCCCATTTGGAGGCCAGCGCTGAGAAGTGGAACAGGTTGCTGATGTC
CTTAGAAGAACTGATCAAATGGCTGAATATGAAAGATGAAGAGCTTAAGAAACAAATGCCTATTGGAGGA
GATGTTCCAGCCTTACAGCTCCAGTATGACCATTGTAAGGCCCTGAGACGGGAGTTAAAGGAGAAAGAAT
ATTCTGTCCTGAATGCTGTCGACCAGGCCCGAGTTTTCTTGGCTGATCAGCCAATTGAGGCCCCTGAAGA
GCCAAGAAGAAACCTACAATCAAAAACAGAATTAACTCCTGAGGAGAGAGCCCAAAAGATTGCCAAAGCC
ATGCGCAAACAGTCTTCTGAAGTCAAAGAAAAATGGGAAAGTCTAAATGCTGTAACTAGCAATTGGCAAA
AGCAAGTGGACAAGGCATTGGAGAAACTCAGAGACCTGCAGGGAGCTATGGATGACCTGGACGCTGACAT
GAAGGAGGCAGAGTCCGTGCGGAATGGCTGGAAGCCCGTGGGAGACTTACTCATTGACTCGCTGCAGGAT
CACATTGAAAAAATCATGGCATTTAGAGAAGAAATTGCACCAATCAACTTTAAAGTTAAAACGGTGAATG
ATTTATCCAGTCAGCTGTCTCCACTTGACCTGCATCCCTCTCTAAAGATGTCTCGCCAGCTAGATGACCT
TAATATGCGATGGAAACTTTTACAGGTTTCTGTGGATGATCGCCTTAAACAGCTTCAGGAAGCCCACAGA
GATTTTGGACCATCCTCTCAGCATTTTCTCTCTACGTCAGTCCAGCTGCCGTGGCAAAGATCCATTTCAC
ATAATAAAGTGCCCTATTACATCAACCATCAAACACAGACCACCTGTTGGGACCATCCTAAAATGACCGA
ACTCTTTCAATCCCTTGCTGACCTGAATAATGTACGTTTTTCTGCCTACCGTACAGCAATCAAAATCCGA
AGACTACAAAAAGCACTATGTTTGGATCTCTTAGAGTTGAGTACAACAAATGAAATTTTCAAACAGCACA
AGTTGAACCAAAATGACCAGCTCCTCAGTGTTCCAGATGTCATCAACTGTCTGACAACAACTTATGATGG
ACTTGAGCAAATGCATAAGGACCTGGTCAACGTTCCACTCTGTGTTGATATGTGTCTCAATTGGTTGCTC
AATGTCTATGACACGGGTCGAACTGGAAAAATTAGAGTGCAGAGTCTGAAGATTGGATTAATGTCTCTCT
CCAAAGGTCTCTTGGAAGAAAAATACAGATATCTCTTTAAGGAAGTTGCAGGGCCAACAGAAATGTGTGA
CCAGAGGCAGCTGGGCCTGTTACTTCATGATGCCATCCAGATCCCCCGGCAGCTAGGTGAAGTAGCAGCT
TTTGGAGGCAGTAATATTGAGCCTAGTGTTCGCAGCTGCTTCCAACAGAATAACAATAAACCAGAAATAA
GTGTGAAAGAGTTTATAGATTGGATGCATTTGGAACCACAGTCCATGGTTTGGCTCCCAGTTTTACATCG
AGTGGCAGCAGCGGAGACTGCAAAACATCAGGCCAAATGCAACATCTGTAAAGAATGTCCAATTGTCGGG
TTCAGGTATAGAAGCCTTAAGCATTTTAACTATGATGTCTGCCAGAGTTGTTTCTTTTCGGGTCGAACAG
CAAAAGGTCACAAATTACATTACCCAATGGTGGAATATTGTATACCTACAACATCTGGGGAAGATGTACG
AGACTTCACAAAGGTACTTAAGAACAAGTTCAGGTCGAAGAAGTACTTTGCCAAACACCCTCGACTTGGT
TACCTGCCTGTCCAGACAGTTCTTGAAGGTGACAACTTAGAGACTCCTATCACACTCATCAGTATGTGGC
CAGAGCACTATGACCCCTCACAATCTCCTCAACTGTTTCATGATGACACCCATTCAAGAATAGAACAATA
TGCCACACGACTGGCCCAGATGGAAAGGACTAATGGGTCTTTTCTCACTGATAGCAGCTCCACCACAGGA
AGTGTGGAAGACGAGCACGCCCTCATCCAGCAGTATTGCCAAACACTCGGAGGAGAGTCCCCAGTGAGCC
AGCCGCAGAGCCCAGCTCAGATCCTGAAGTCAGTAGAGAGGGAAGAACGTGGAGAACTGGAGAGGATCAT
TGCTGACCTGGAGGAAGAACAAAGAAATCTACAGGTGGAGTATGAGCAGCTGAAGGACCAGCACCTCCGA
AGGGGGCTCCCTGTCGGTTCACCGCCAGAGTCGATTATATCTCCCCATCACACGTCTGAGGATTCAGAAC
TTATAGCAGAAGCAAAACTCCTCAGGCAGCACAAAGGTCGGCTGGAGGCTAGGATGCAGATTTTAGAAGA
TCACAATAAACAGCTGGAGTCTCAGCTCCACCGCCTCCGACAGCTGCTGGAGCAGCCTGAATCTGATTCC
CGAATCAATGGTGTTTCCCCATGGGCTTCTCCTCAGCATTCTGCACTGAGCTACTCGCTTGATCCAGATG
CCTCCGGCCCACAGTTCCACCAGGCAGCGGGAGAGGACCTGCTGGCCCCACCGCACGACACCAGCACGGA
TCTCACGGAGGTCATGGAGCAGATTCACAGCACGTTTCCATCTTGCTGCCCAAATGTTCCCAGCAGGCCA
CAGGCAATGTGA

翻译后氨基酸参数序列： 点击查看序列

ATGGCCAAGTATGGAGAACATGAAGCCAGTCCTGACAATGGGCAGAACGAATTCAGTGATATCATTAAGT
CCAGATCTGATGAACACAATGACGTACAGAAGAAAACCTTTACCAAATGGATAAATGCTCGATTTTCAAA
GAGTGGGAAACCACCCATCAATGATATGTTCACAGACCTCAAAGATGGAAGGAAGCTATTGGATCTTCTA
GAAGGCCTCACAGGAACATCACTGCCAAAGGAACGTGGTTCCACAAGGGTACATGCCTTAAATAACGTCA
ACAGAGTGCTGCAGGTTTTACATCAGAACAATGTGGAATTAGTGAATATAGGGGGAACTGACATTGTGGA
TGGAAATCACAAACTGACTTTGGGGTTACTTTGGAGCATCATTTTGCACTGGCAGGTGAAAGATGTCATG
AAGGATGTCATGTCGGACCTGCAGCAGACGAACAGTGAGAAGATCCTGCTCAGCTGGGTGCGTCAGACCA
CCAGGCCCTACAGCCAAGTCAACGTCCTCAACTTCACCACCAGCTGGACAGATGGACTCGCCTTTAATGC
TGTCCTCCACCGACATAAACCTGATCTCTTCAGCTGGGATAAAGTTGTCAAAATGTCACCAATTGAGAGA
CTTGAACATGCCTTCAGCAAGGCTCAAACTTATTTGGGAATTGAAAAGCTGTTAGATCCTGAAGATGTTG
CCGTTCAGCTTCCTGACAAGAAATCCATAATTATGTATTTAACATCTTTGTTTGAGGTGCTACCTCAGCA
AGTCACCATAGACGCCATCCGTGAGGTAGAGACACTCCCAAGGAAATATAAAAAAGAATGTGAAGAAGAG
GCAATTAATATACAGAGTACAGCGCCTGAGGAGGAGCATGAGAGTCCCCGAGCTGAAACTCCCAGCACTG
TCACTGAGGTTGACATGGATCTGGACAGCTATCAGATTGCGTTGGAGGAAGTGCTGACCTGGTTGCTTTC
TGCTGAGGACACTTTCCAGGAGCAGGATGATATTTCTGATGATGTTGAAGAAGTCAAAGACCAGTTTGCA
ACCCATGAAGCTTTTATGATGGAACTGACTGCACACCAGAGCAGTGTGGGCAGCGTCCTGCAGGCAGGCA
ACCAACTGATAACACAAGGAACTCTGTCAGACGAAGAAGAATTTGAGATTCAGGAACAGATGACCCTGCT
GAATGCTAGATGGGAGGCTCTTAGGGTGGAGAGTATGGACAGACAGTCCCGGCTGCACGATGTGCTGATG
GAACTGCAGAAGAAGCAACTGCAGCAGCTCTCCGCCTGGTTAACACTCACAGAGGAGCGCATTCAGAAGA
TGGAAACTTGCCCCCTGGATGATGATGTAAAATCTCTACAAAAGCTGCTAGAAGAACATAAAAGTTTGCA
AAGTGATCTTGAGGCTGAACAGGTGAAAGTAAATTCACTAACTCACATGGTGGTCATTGTTGATGAAAAC
AGTGGTGAGAGTGCTACAGCTATCCTAGAAGACCAGTTACAGAAACTTGGTGAGCGCTGGACAGCAGTAT
GCCGTTGGACTGAAGAACGCTGGAATAGGTTACAAGAAATCAATATATTGTGGCAGGAATTATTGGAAGA
ACAGTGCTTGTTGAAAGCTTGGTTAACCGAAAAAGAAGAGGCTTTAAATAAAGTCCAGACAAGCAACTTC
AAAGACCAAAAGGAACTAAGTGTCAGTGTTCGACGTCTGGCTATTTTGAAGGAAGACATGGAAATGAAGC
GTCAAACATTGGATCAGCTGAGTGAGATTGGCCAGGATGTGGGACAATTACTTGATAATTCCAAGGCATC
TAAGAAGATCAACAGTGACTCAGAGGAACTGACTCAAAGATGGGATTCTTTGGTTCAGAGACTAGAAGAT
TCCTCCAACCAGGTGACTCAGGCTGTAGCAAAGCTGGGGATGTCTCAGATTCCTCAGAAGGACCTTTTGG
AGACTGTTCGTGTAAGAGAACAAGCAATTACAAAAAAATCTAAGCAGGAACTGCCTCCTCCTCCTCCCCC
AAAGAAGAGACAGATCCATGTGGATATTGAAGCTAAGAAAAAGTTTGATGCTATAAGTGCAGAGCTGTTG
AACTGGATTTTGAAATGGAAAACTGCCATTCAGACCACAGAGATAAAAGAGTATATGAAGATGCAAGACA
CTTCCGAAATGAAAAAGAAGTTGAAGGCATTAGAAAAAGAACAGAGAGAAAGAATCCCCAGAGCAGATGA
ATTAAACCAAACTGGACAAATCCTTGTGGAGCAAATGGGAAAAGAAGGCCTTCCTACTGAAGAAATAAAA
AATGTTCTGGAGAAGGTTTCATCAGAATGGAAGAATGTATCTCAACATTTGGAAGATCTAGAAAGAAAGA
TTCAGCTACAGGAAGATATAAATGCTTATTTCAAGCAGCTTGATGAGCTTGAAAAGGTCATCAAGACAAA
GGAGGAGTGGGTAAAACACACTTCCATTTCTGAATCTTCCCGGCAGTCCTTGCCAAGCTTGAAGGATTCC
TGTCAGCGGGAATTGACAAATCTTCTTGGCCTTCACCCCAAAATTGAAATGGCTCGTGCAAGCTGCTCGG
CCCTGATGTCTCAGCCTTCTGCCCCAGATTTTGTCCAGCGGGGCTTCGATAGCTTTCTGGGCCGCTACCA
AGCTGTACAAGAGGCTGTAGAGGATCGTCAACAACATCTAGAGAATGAACTGAAGGGCCAACCTGGACAT
GCATATCTGGAAACATTGAAAACACTGAAAGATGTGCTAAATGATTCAGAAAATAAGGCCCAGGTGTCTC
TGAATGTCCTTAATGATCTTGCCAAGGTGGAGAAGGCCCTGCAAGAAAAAAAGACCCTTGATGAAATCCT
TGAGAATCAGAAACCTGCATTACATAAACTTGCAGAAGAAACAAAGGCTCTGGAGAAAAATGTTCATCCT
GATGTAGAAAAATTATATAAGCAAGAATTTGATGATGTGCAAGGAAAGTGGAACAAGCTAAAGGTCTTGG
TTTCCAAAGATCTACATTTGCTTGAGGAAATTGCTCTCACACTCAGAGCTTTTGAGGCCGATTCAACAGT
CATTGAGAAGTGGATGGATGGCGTGAAAGACTTCTTAATGAAACAGCAGGCTGCCCAAGGAGACGACGCA
GGTCTACAGAGGCAGTTAGACCAGTGCTCTGCATTTGTTAATGAAATAGAAACAATTGAATCATCTCTGA
AAAACATGAAGGAAATAGAGACTAATCTTCGAAGTGGTCCAGTTGCTGGAATAAAAACTTGGGTGCAGAC
AAGACTAGGTGACTACCAAACTCAACTGGAGAAACTTAGCAAGGAGATCGCTACTCAAAAAAGTAGGTTG
TCTGAAAGTCAAGAAAAAGCTGCGAACCTGAAGAAAGACTTGGCAGAGATGCAGGAATGGATGACCCAGG
CCGAGGAAGAATATTTGGAGCGGGATTTTGAGTACAAGTCACCAGAAGAGCTTGAGAGTGCTGTGGAAGA
GATGAAGAGGGCAAAAGAGGATGTGTTGCAGAAGGAGGTGAGAGTGAAGATTCTCAAGGACAACATCAAG
TTATTAGCTGCCAAGGTGCCCTCTGGTGGCCAGGAGTTGACGTCTGAGCTGAATGTTGTGCTGGAGAATT
ACCAACTTCTTTGTAATAGAATTCGAGGAAAGTGCCACACGCTAGAGGAGGTCTGGTCTTGTTGGATTGA
ACTGCTTCACTATTTGGATCTTGAAACTACCTGGTTAAACACTTTGGAAGAGCGGATGAAGAGCACAGAG
GTCCTGCCTGAGAAGACGGATGCTGTCAACGAAGCCCTGGAGTCTCTGGAATCTGTTCTGCGCCACCCGG
CAGATAATCGCACCCAGATTCGAGAGCTTGGCCAGACTCTGATTGATGGGGGGATCCTGGATGATATAAT
CAGTGAGAAACTGGAGGCTTTCAACAGCCGATATGAAGATCTAAGTCACCTGGCAGAGAGCAAGCAGATT
TCTTTGGAAAAGCAACTCCAGGTGCTGCGGGAAACTGACCAGATGCTTCAAGTCTTGCAAGAGAGCTTGG
GGGAGCTGGACAAACAGCTCACCACATACCTGACTGACAGGATAGATGCTTTCCAAGTTCCACAGGAAGC
TCAGAAAATCCAAGCAGAGATCTCAGCCCATGAGCTAACCCTAGAGGAGTTGAGAAGAAATATGCGTTCT
CAGCCCCTGACCTCCCCAGAGAGTAGGACTGCCAGAGGAGGAAGTCAGATGGATGTGCTACAGAGGAAAC
TCCGAGAGGTGTCCACAAAGTTCCAGCTTTTCCAGAAGCCAGCTAACTTCGAGCAGCGCATGCTGGACTG
CAAGCGTGTGCTGGATGGCGTGAAAGCAGAACTTCACGTTCTGGATGTGAAGGACGTAGACCCTGACGTC
ATACAGACGCACCTGGACAAGTGTATGAAACTGTATAAAACTTTGAGTGAAGTCAAACTTGAAGTGGAAA
CTGTGATTAAAACAGGAAGACATATTGTCCAGAAACAGCAAACGGACAACCCAAAAGGGATGGATGAGCA
GCTGACTTCCCTGAAGGTTCTTTACAATGACCTGGGCGCACAGGTGACAGAAGGAAAACAGGATCTGGAA
AGAGCATCACAGTTGGCCCGGAAAATGAAGAAAGAGGCTGCTTCTCTCTCTGAATGGCTTTCTGCTACTG
AAACTGAATTGGTACAGAAGTCCACTTCAGAAGGTCTGCTTGGTGACTTGGATACAGAAATTTCCTGGGC
TAAAAATGTTCTGAAGGATCTGGAAAAGAGAAAAGCTGATTTAAATACCATCACAGAGAGTAGTGCTGCC
CTGCAAAACTTGATTGAGGGCAGTGAGCCTATTTTAGAAGAGAGGCTCTGCGTCCTTAACGCTGGGTGGA
GCCGAGTTCGTACCTGGACTGAAGATTGGTGCAATACCTTGATGAACCATCAGAACCAGCTAGAAATATT
TGATGGGAACGTGGCTCACATAAGTACCTGGCTTTATCAAGCTGAAGCTCTATTGGATGAAATTGAAAAG
AAACCAACAAGTAAACAGGAAGAAATTGTGAAGCGTTTAGTATCTGAGCTGGATGATGCCAACCTCCAGG
TTGAAAATGTCCGCGATCAAGCCCTTATTTTGATGAATGCCCGTGGAAGCTCAAGCAGGGAGCTTGTAGA
ACCAAAGTTAGCTGAGCTGAATAGGAACTTTGAAAAGGTGTCTCAACATATCAAAAGTGCCAAATTGCTA
ATTGCTCAGGAACCATTATACCAATGTTTGGTCACCACTGAAACATTTGAAACTGGTGTGCCTTTCTCTG
ACTTGGAAAAATTAGAAAATGACATAGAAAATATGTTAAAATTTGTGGAAAAACACTTGGAATCCAGTGA
TGAAGATGAAAAGATGGATGAGGAGAGTGCCCAGATTGAGGAAGTTCTACAAAGAGGAGAAGAAATGTTA
CATCAACCTATGGAAGATAATAAAAAAGAAAAGATCCGTTTGCAATTATTACTTTTGCATACTAGATACA
ACAAAATTAAGGCAATCCCTATTCAACAGAGGAAAATGGGTCAACTTGCTTCTGGAATTAGATCATCACT
TCTTCCTACAGATTATCTGGTTGAAATTAACAAAATTTTACTTTGCATGGATGATGTTGAATTATCGCTT
AATGTTCCAGAGCTCAACACTGCTATTTACGAAGACTTCTCTTTTCAGGAAGACTCTCTGAAGAATATCA
AAGACCAACTGGACAAACTTGGAGAGCAGATTGCAGTCATTCATGAAAAACAGCCAGATGTCATCCTTGA
AGCCTCTGGACCTGAAGCCATTCAGATCAGAGATACACTTACTCAGCTGAATGCAAAATGGGACAGAATT
AATAGAATGTACAGTGATCGGAAAGGTTGTTTTGACAGGGCAATGGAAGAATGGAGACAGTTCCATTGTG
ACCTTAATGACCTCACACAGTGGATAACAGAGGCTGAAGAATTACTGGTTGATACCTGTGCTCCAGGTGG
CAGCCTGGACTTAGAGAAAGCCAGGATACATCAGCAGGAACTTGAGGTGGGCATCAGCAGCCACCAGCCC
AGTTTTGCAGCACTAAACCGAACTGGGGATGGGATTGTGCAGAAACTCTCCCAGGCAGATGGAAGCTTCT
TGAAAGAAAAACTGGCAGGTTTAAACCAACGCTGGGATGCAATTGTTGCAGAAGTGAAGGATAGGCAGCC
AAGGCTAAAAGGAGAAAGTAAGCAGGTGATGAAGTACAGGCATCAGCTAGATGAGATTATCTGTTGGTTA
ACAAAGGCTGAGCATGCTATGCAAAAGAGATCAACCACCGAATTGGGAGAAAACCTGCAAGAATTAAGAG
ACTTAACTCAAGAAATGGAAGTACATGCTGAAAAACTCAAATGGCTGAATAGAACTGAATTGGAGATGCT
TTCAGATAAAAGTCTGAGTTTACCTGAAAGGGATAAAATTTCAGAAAGCTTAAGGACTGTAAATATGACA
TGGAATAAGATTTGCAGAGAGGTGCCTACCACCCTGAAGGAATGCATCCAGGAGCCCAGTTCTGTTTCAC
AGACAAGGATTGCTGCTCATCCTAATGTCCAAAAGGTGGTGCTAGTATCATCTGCGTCAGATATTCCTGT
TCAGTCTCATCGTACTTCGGAAATTTCAATTCCTGCTGATCTTGATAAAACTATAACAGAACTAGCCGAC
TGGCTGGTATTAATCGACCAGATGCTGAAGTCCAACATTGTCACTGTTGGGGATGTAGAAGAGATCAATA
AGACCGTTTCCCGAATGAAAATTACAAAGGCTGACTTAGAACAGCGCCATCCTCAGCTGGATTATGTTTT
TACATTGGCACAGAATTTGAAAAATAAAGCTTCCAGTTCAGATATGAGAACAGCAATTACAGAAAAATTG
GAAAGGGTCAAGAACCAGTGGGATGGCACCCAGCATGGCGTTGAGCTAAGACAGCAGCAGCTTGAGGACA
TGATTATTGACAGTCTTCAGTGGGATGACCATAGGGAGGAGACTGAAGAACTGATGAGAAAATATGAGGC
TCGACTCTATATTCTTCAGCAAGCCCGACGGGATCCACTCACCAAACAAATTTCTGATAACCAAATACTG
CTTCAAGAACTGGGTCCTGGAGATGGTATCGTCATGGCGTTCGATAACGTCCTGCAGAAACTCCTGGAGG
AATATGGGAGTGATGACACAAGGAATGTGAAAGAAACCACAGAGTACTTAAAAACATCATGGATCAATCT
CAAACAAAGTATTGCTGACAGACAGAACGCCTTGGAGGCTGAGTGGAGGACGGTGCAGGCCTCTCGCAGA
GATCTGGAAAACTTCCTGAAGTGGATCCAAGAAGCAGAGACCACAGTGAATGTGCTTGTGGATGCCTCTC
ATCGGGAGAATGCTCTTCAGGATAGTATCTTGGCCAGGGAACTCAAACAGCAGATGCAGGACATCCAGGC
AGAAATTGATGCCCACAATGACATATTTAAAAGCATTGACGGAAACAGGCAGAAGATGGTAAAAGCTTTG
GGAAATTCTGAAGAGGCTACTATGCTTCAACATCGACTGGATGATATGAACCAAAGATGGAATGACTTAA
AAGCAAAATCTGCTAGCATCAGGGCCCATTTGGAGGCCAGCGCTGAGAAGTGGAACAGGTTGCTGATGTC
CTTAGAAGAACTGATCAAATGGCTGAATATGAAAGATGAAGAGCTTAAGAAACAAATGCCTATTGGAGGA
GATGTTCCAGCCTTACAGCTCCAGTATGACCATTGTAAGGCCCTGAGACGGGAGTTAAAGGAGAAAGAAT
ATTCTGTCCTGAATGCTGTCGACCAGGCCCGAGTTTTCTTGGCTGATCAGCCAATTGAGGCCCCTGAAGA
GCCAAGAAGAAACCTACAATCAAAAACAGAATTAACTCCTGAGGAGAGAGCCCAAAAGATTGCCAAAGCC
ATGCGCAAACAGTCTTCTGAAGTCAAAGAAAAATGGGAAAGTCTAAATGCTGTAACTAGCAATTGGCAAA
AGCAAGTGGACAAGGCATTGGAGAAACTCAGAGACCTGCAGGGAGCTATGGATGACCTGGACGCTGACAT
GAAGGAGGCAGAGTCCGTGCGGAATGGCTGGAAGCCCGTGGGAGACTTACTCATTGACTCGCTGCAGGAT
CACATTGAAAAAATCATGGCATTTAGAGAAGAAATTGCACCAATCAACTTTAAAGTTAAAACGGTGAATG
ATTTATCCAGTCAGCTGTCTCCACTTGACCTGCATCCCTCTCTAAAGATGTCTCGCCAGCTAGATGACCT
TAATATGCGATGGAAACTTTTACAGGTTTCTGTGGATGATCGCCTTAAACAGCTTCAGGAAGCCCACAGA
GATTTTGGACCATCCTCTCAGCATTTTCTCTCTACGTCAGTCCAGCTGCCGTGGCAAAGATCCATTTCAC
ATAATAAAGTGCCCTATTACATCAACCATCAAACACAGACCACCTGTTGGGACCATCCTAAAATGACCGA
ACTCTTTCAATCCCTTGCTGACCTGAATAATGTACGTTTTTCTGCCTACCGTACAGCAATCAAAATCCGA
AGACTACAAAAAGCACTATGTTTGGATCTCTTAGAGTTGAGTACAACAAATGAAATTTTCAAACAGCACA
AGTTGAACCAAAATGACCAGCTCCTCAGTGTTCCAGATGTCATCAACTGTCTGACAACAACTTATGATGG
ACTTGAGCAAATGCATAAGGACCTGGTCAACGTTCCACTCTGTGTTGATATGTGTCTCAATTGGTTGCTC
AATGTCTATGACACGGGTCGAACTGGAAAAATTAGAGTGCAGAGTCTGAAGATTGGATTAATGTCTCTCT
CCAAAGGTCTCTTGGAAGAAAAATACAGATATCTCTTTAAGGAAGTTGCAGGGCCAACAGAAATGTGTGA
CCAGAGGCAGCTGGGCCTGTTACTTCATGATGCCATCCAGATCCCCCGGCAGCTAGGTGAAGTAGCAGCT
TTTGGAGGCAGTAATATTGAGCCTAGTGTTCGCAGCTGCTTCCAACAGAATAACAATAAACCAGAAATAA
GTGTGAAAGAGTTTATAGATTGGATGCATTTGGAACCACAGTCCATGGTTTGGCTCCCAGTTTTACATCG
AGTGGCAGCAGCGGAGACTGCAAAACATCAGGCCAAATGCAACATCTGTAAAGAATGTCCAATTGTCGGG
TTCAGGTATAGAAGCCTTAAGCATTTTAACTATGATGTCTGCCAGAGTTGTTTCTTTTCGGGTCGAACAG
CAAAAGGTCACAAATTACATTACCCAATGGTGGAATATTGTATACCTACAACATCTGGGGAAGATGTACG
AGACTTCACAAAGGTACTTAAGAACAAGTTCAGGTCGAAGAAGTACTTTGCCAAACACCCTCGACTTGGT
TACCTGCCTGTCCAGACAGTTCTTGAAGGTGACAACTTAGAGACTCCTATCACACTCATCAGTATGTGGC
CAGAGCACTATGACCCCTCACAATCTCCTCAACTGTTTCATGATGACACCCATTCAAGAATAGAACAATA
TGCCACACGACTGGCCCAGATGGAAAGGACTAATGGGTCTTTTCTCACTGATAGCAGCTCCACCACAGGA
AGTGTGGAAGACGAGCACGCCCTCATCCAGCAGTATTGCCAAACACTCGGAGGAGAGTCCCCAGTGAGCC
AGCCGCAGAGCCCAGCTCAGATCCTGAAGTCAGTAGAGAGGGAAGAACGTGGAGAACTGGAGAGGATCAT
TGCTGACCTGGAGGAAGAACAAAGAAATCTACAGGTGGAGTATGAGCAGCTGAAGGACCAGCACCTCCGA
AGGGGGCTCCCTGTCGGTTCACCGCCAGAGTCGATTATATCTCCCCATCACACGTCTGAGGATTCAGAAC
TTATAGCAGAAGCAAAACTCCTCAGGCAGCACAAAGGTCGGCTGGAGGCTAGGATGCAGATTTTAGAAGA
TCACAATAAACAGCTGGAGTCTCAGCTCCACCGCCTCCGACAGCTGCTGGAGCAGCCTGAATCTGATTCC
CGAATCAATGGTGTTTCCCCATGGGCTTCTCCTCAGCATTCTGCACTGAGCTACTCGCTTGATCCAGATG
CCTCCGGCCCACAGTTCCACCAGGCAGCGGGAGAGGACCTGCTGGCCCCACCGCACGACACCAGCACGGA
TCTCACGGAGGTCATGGAGCAGATTCACAGCACGTTTCCATCTTGCTGCCCAAATGTTCCCAGCAGGCCA
CAGGCAATGTGA