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- accession：NM_001145769
- 基因别名：XP3; RAD4; XPCC
- 基因描述：Homo sapiens xeroderma pigmentosum, complementation group C (XPC), transcript variant 2, mRNA.
- 载体：现货载体
- CDS区长度：2712
- 翻译后氨基酸长度：903
- TranscriptVariant：This variant (2) lacks an internal segment in the CDS, as compared to variant 1. The reading frame is not changed, and the resulting isoform (2) is shorter than isoform 1.
- 基因简介：This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
